Patents by Inventor Nicholas Bonham

Nicholas Bonham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of (R)-5-[3-chloro-4-(2,3-dihydroxy-propoxy)-benz[Z]ylidene]-2-([Z]-propylimino)-3-0-tolyl-thiazolidin-4-one
    Patent number: 9062014
    Abstract: The invention relates to crystalline forms of (R)-5-[3-chloro-4-(2,3-dihydroxy-propoxy)-benz[Z]ylidene]-2-([Z]-propylimino)-3-o-tolyl-thiazolidin-4-one, processes for the preparation thereof, pharmaceutical compositions containing said crystalline forms, and their use as compounds improving vascular function and as immunomodulating agents, either alone or in combination with other active compounds or therapies.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: June 23, 2015
    Assignee: ACTELION PHARMACEUTICALS LTD.
    Inventors: Nicholas Bonham, Stephan Buchmann, Alex Eberlin, Christoph Imboden, Markus Von Raumer
  • CRYSTALLINE FORMS OF (R) -5-[3-CHLORO-4-(2,3-DIHYDROXY-PROPOXY)-BENZ [Z] YLIDENE] -2-( [Z]-PROPYLIMINO) -3-0-TOLYL-THIAZOLIDIN-4-ONE
    Publication number: 20110196004
    Abstract: The invention relates to crystalline forms of (R)-5-[3-chloro-4-(2,3-dihydroxy-propoxy)-benz[Z]ylidene]-2-([Z]-propylimino)-3-o-tolyl-thiazolidin-4-one, processes for the preparation thereof, pharmaceutical compositions containing said crystalline forms, and their use as compounds improving vascular function and as immunomodulating agents, either alone or in combination with other active compounds or therapies.
    Type: Application
    Filed: October 19, 2009
    Publication date: August 11, 2011
    Inventors: Nicholas Bonham, Stephan Buchmann, Alex Eberlin, Christoph Imboden, Markus Von Raumer
  • Method of reclaiming drug compound from liposomal drug manufacturing stream
    Publication number: 20060159735
    Abstract: A method of forming a liposomal pharmaceutical composition containing the compound: from a feedstock solution of the compound, comprises the steps of assaying a permeate wash for HSPC and cholesterol; processing the permeate wash to form a concentrated solution of the compound if the assay result is lower or equal to a predetermined value; and adding the concentrated solution to the feedstock solution.
    Type: Application
    Filed: January 20, 2005
    Publication date: July 20, 2006
    Inventors: Nicholas Bonham, Janet Poole, Andrew Wilkins