Abstract: Temporary vascular occlusion devices and methods for use thereof are described which provide temporary vascular occlusion while maintaining distal perfusion along with vascular access. The temporary vascular occlusion device may include a multiple layer scaffold covering having proximal and distal attachment zones separated by an unattached scaffold covering zone where the scaffold covering is adjacent to but not attached directly to the scaffold frame. Devices for a vascular procedure may access the vasculature using a guide catheter in the shaft of the occlusion device. The occlusion device may then be used to provide protection from contrast media used during the vascular procedure conducted using the access provided by the occlusion device.

Abstract: Various features are described that are adapted to improve performance of interference-relief type delivery systems. A delivery system provided herein comprises an implant comprising a socket at a proximal end of the implant; an elongate sleeve having (i) a proximal section, (ii) a distal section slidably disposed within the socket, and (iii) a window between the proximal section and the distal section, the window extending through a wall of the sleeve; and a core member having a proximal portion slidably received within the proximal section of the sleeve and a distal portion extending through the window to a space outside the sleeve and within the socket. The distal portion of the core member provides an interference fit with the distal section of the sleeve within the socket until the core member is withdrawn.

Abstract: Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The subject implants are deployed in two stages. If sized properly as observed in the first stage, they are deployed to the second stage and detached. If not sized properly in/at the first stage, the implants are designed to be withdrawn and replaced with a more appropriately sized implant or another treatment option selected. Some of the implant configurations may be withdrawn even after the second stage deployment as well.

Abstract: A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. Alternatively, a system includes a lead, a lead body, at least one electrode; with a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.

Abstract: Embolic implants and methods of manufacture are disclosed. The implants may be used for occluding blood flow at endovascular sites. One use is in intracranial aneurysm emolization/occlusion and another in parent vessel occlusion (PVO) or sacrifice. Various features provide for improved use (e.g., regarding delivery, recapture, visualization and/or occlusion) and manufacturability.

Abstract: A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. A system includes a lead having a lead body and at least one electrode; and a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue when the lead is positioned in a body. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.

Abstract: Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The subject implants are deployed in two stages. If sized properly as observed in the first stage, they are deployed to the second stage and detached. If not sized properly in/at the first stage, the implants are designed to be withdrawn and replaced with a more appropriately sized implant or another treatment option selected. Some of the implant configurations may be withdrawn even after the second stage deployment as well.

Abstract: Disc brake rotors in which figural bodies are formed by struts connecting an inner hub mounting section to an outer braking surface section are described. An entertaining variety of forms may be so-portrayed. Additional graphical features may be applied or incorporated, for example, in the outer ring of the rotor.

Abstract: Embolic implants and methods of manufacture are disclosed. The implants may be used for occluding blood flow at endovascular sites. One use is in intracranial aneurysm emolization/occlusion and another in parent vessel occlusion (PVO) or sacrifice. Various features provide for improved use (e.g., regarding delivery, recapture, visualization and/or occlusion) and manufacturability.

Abstract: Embolic implants and methods of manufacture are disclosed. The implants may be used for occluding blood flow at endovascular sites. One use is in intracranial aneurysm emolization/occlusion and another in parent vessel occlusion (PVO) or sacrifice. Various features provide for improved use (e.g., regarding delivery, recapture, visualization and/or occlusion) and manufacturability.

Abstract: An implant for treating brain aneurysms, especially terminal aneurysms, comprises a neck cover and elongate shaft removably secured to an embolic delivery catheter. As such, the shaft aids in directing and placing the cover at the aneurysm neck, protecting the delivery catheter from adhesion with the embolic material, and securing the cover in place with connection or adhesion of the shaft to the embolic material delivered through the catheter. The implant can be anchored at the aneurysm either by interface and/or adhesion of the shaft or shaft and cover with the resident embolic materials.

Abstract: High performance guide catheters are described as suitable for neurovascular access. They are constructed using a machined core, in which the core includes transition features from a proximal to distal-most section of the device.

Abstract: Medical devices (100) and methods for delivery or implantation of prostheses (106) within hollow body organs and vessels (600) or other luminal anatomy are disclosed. The subject technologies may be used in the treatment of atherosclerosis in stenting procedures or for other purposes.

Abstract: Medical device and methods for delivery or implantation of prostheses within hollow body organs and vessels or other luminal anatomy are disclosed. The subject technologies may be used in the treatment of atherosclerosis in stenting procedures. For such purposes, a self-expanding stent is deployed in connection with an angioplasty procedure with a corewire actuated delivery system having a fixed distal stent-carrying extension. Withdrawal of the corewire retracts a restraint freeing the stent from a collapsed state, whereupon the stent assumes an expanded configuration set in apposition to the interior surface of a vessel lumen in order to help maintain the vessel open.

Abstract: The subjected devices include a stent, a graft and a means for attaching the graft to the stent. One or more members are received in a permanent or temporary receptacle within the stent attach the graft to the stent. In one variation, an interference fit is employed; in another, the graft is bonded to a stent-captured member(s).

Abstract: An anti-restontic device is provided for repairing a tissue, particularly an arteriosclerosed blood vessel or a damaged wall of a luminal or chambered organ. In some embodiments, the device comprises a structure having a first surface and a second surface. A bioactive layer is disposed on the first surface, wherein the bioactive layer enhances growth of a type of cells thereon. And an anti-restenosis layer is disposed on the second surface, wherein the anti-restenosis layer inhibits growth of another type of cells thereon.

Abstract: Disc brake rotors in which figural bodies are formed by struts connecting an inner hub mounting section to an outer braking surface section are described. An entertaining variety of forms may be so-portrayed. Additional graphical features may be applied or incorporated, for example, in the outer ring of the rotor.

Abstract: A system includes a lead having a lead body and at least one electrode; and a retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in atraumatically anchoring the lead to nearby tissue when the lead is positioned in the body. A system includes a lead having a lead body and at least one electrode; and a coiled retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the lead to nearby tissue when the lead is positioned in a body. A lead for stimulating a target neural tissue includes an elongate body; at least one electrode disposed along the elongate body; and a passive retention feature disposed along the lead body proximal to the at least one electrode and configured to assist in anchoring the elongate body to tissue near the target neural tissue.

Abstract: The shape memory polymer stent or intravascular flow modifier is made from a polymer having shape memory properties so as to be self expanding. The stent can be formed as an extruded tube having a truss-like design, and formed from a polymer having shape memory properties, or can be formed as a tube woven from extruded strands of a polymer having shape memory properties. The stent of the invention can be compressed over a mounting portion of a pusher catheter for deployment within the vasculature. The stent can then be inserted into the vasculature and maneuvered into a desired location mounted on the pusher catheter, and heat can be transferred to the stent from the pusher catheter to cause the stent to radially expand and axially retract to deploy the stent in the vasculature, and allow the pusher catheter to be retracted from the vasculature.

Abstract: An embodiment of a placement catheter assembly (2) comprises an inner shaft (10) movably housed within a hollow outer shaft (8). A radially-expansible endoluminal prosthesis (6) is mounted about the inner shaft between the distal ends of the inner and outer shafts. Distal and proximal end release elements (22/28, 16/34), such as pull wires, are carried by the inner and outer shafts and releasably secure the prosthesis to the inner and outer shafts. The prosthesis in the radially contracted state and the distal and proximal end release elements together have a maximum diameter which is at most about equal to the diameter of the distal part (48) of the outer shaft to facilitate placement of the prosthesis.