Abstract: Disclosed herein are compounds selective for JAK1, pharmaceutical compositions comprising said compounds, and methods of using said compounds.

Abstract: In various examples, network conditions associated with a video stream are observed over time to determine a virtual scaling factor that may be applied to the images of one or more frames of the video stream to generate scaled images that may be appended with a padding region that maintains the original resolution of the video and/or video stream such that a receiving device may crop the padding region from the received video stream during the decoding process without restarting or including additional intra-coded frames.

Abstract: Examples of the present disclosure relate to a device, method, and system for integrating a projection mode of a user mobile device with a terrestrial tuner. In an example, the system may be a vehicle including a head unit and a vehicle projection stack to operate in the head unit. The system may also include a terrestrial tuner communicatively coupled to the vehicle projection stack to receive a terrestrial audio signal from a terrestrial source. The system may also include an audio driver to provide an audio signal to a vehicle interior where the audio signal is from at least one of the terrestrial audio signal and an internet audio signal received at the vehicle projection stack from a user mobile device located inside the vehicle interior.

Abstract: The present invention encompasses compounds of the formula (I) wherein the groups A and B are defined herein, which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: The present invention encompasses compounds of the formula (I) wherein the groups A and B are defined herein, which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A method of recording multiple dimensions of a user's movement using a gyroscope-equipped smart device and scoring it relative to a reference recording and/or set of inflection markers for use in dance games, flash mobs, and/or movement training applications.

Abstract: The present invention encompasses compounds of the formula (I) wherein the groups A and B are defined herein, which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A rotary storage device is described. The device comprises a rotatable drum around which media items may be stored, and a tape reel rotatably mounted on a tape reel shaft and partially wound with tape extending from the tape reel to the rotatable drum. The device further comprises a motor coupled to both the rotatable drum and the tape reel shaft. The motor is operable to rotate in a deposit direction and in a dispense direction. The device comprises a friction clutch coupled to both the tape reel shaft and the tape reel to provide some resistance to rotation of the tape reel relative to the tape reel shaft so that the tape reel cannot rotate freely about the tape reel shaft. The device also comprises a one-way clutch coupled to the tape reel shaft to allow the tape reel shaft to rotate in the dispense direction and to prevent the tape reel shaft from rotating in the deposit direction.

Abstract: A media cassette loader is described. The media cassette loader comprises a base; a media loading surface inclined at an angle to the base; and an end wall upstanding from a lower end of the media loading surface. The end wall supports media items stacked on the media loading surface. The media loading surface and the end wall are dimensioned to be accommodated within a media cassette body. This allows the media cassette body to be placed over the media loading surface when stacked with media items so that the cassette body surrounds the stacked media items.

Abstract: A process for providing a corrosion resistant coating on uncoated ferrous components, involving mechanical plating, using as a coating medium a zinc metal-containing powder, such as zinc or zinc alloy powder, or a powder mixture of zinc or zinc alloy and at least one other metal, so as to build up a firmly adherent coating of the coating medium over exposed surfaces of the components, heating the components with the firmly adherent coating to produce solid-solid diffusion to form an Fe/Zn intermetallic over the surfaces, at least in a base layer of the coating built up by the plating, and cooling the components.

Abstract: The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

Abstract: A media cassette loader is described. The media cassette loader comprises a base; a media loading surface inclined at an angle to the base; and an end wall upstanding from a lower end of the media loading surface. The end wall supports media items stacked on the media loading surface. The media loading surface and the end wall are dimensioned to be accommodated within a media cassette body. This allows the media cassette body to be placed over the media loading surface when stacked with media items so that the cassette body surrounds the stacked media items.

Abstract: A media cassette loader is described. The media cassette loader comprises a base; a media loading surface inclined at an angle to the base; and an end wall upstanding from a lower end of the media loading surface. The end wall supports media items stacked on the media loading surface. The media loading surface and the end wall are dimensioned to be accommodated within a media cassette body. This allows the media cassette body to be placed over the media loading surface when stacked with media items so that the cassette body surrounds the stacked media items.

Abstract: Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

Abstract: A process for providing a corrosion resistant coating on uncoated ferrous components, involving mechanical plating, using as a coating medium a zinc metal-containing powder, such as zinc or zinc alloy powder, or a powder mixture of zinc or zinc alloy and at least one other metal, so as to build up a firmly adherent coating of the coating medium over exposed surfaces of the components, heating the components with the firmly adherent coating to produce solid-solid diffusion to form an Fe/Zn intermetallic over the surfaces, at least in a base layer of the coating built up by the plating, and cooling the components

Abstract: Disclosed are CCR1 receptor antagonists of the formula (I) wherein Ar1, Ar2, R1, X and G are disclosed herein. Also disclosed are compositions, methods of making and using compounds of the formula (I).

Abstract: An apparatus and method are disclosed for removing at least one item of media from a rotating drum element. The apparatus includes a scraper element comprising a blade edge region locatable at an effective outer surface of a rotating drum element and a scraper element support that locates the blade edge region at a desired position at the effective outer surface responsive to a diameter of the effective outer surface. The scraper element rotates and moves laterally with respect to the support responsive to the diameter.

Abstract: Disclosed are CCR1 receptor antagonists of the formula (I) wherein Ar1, Ar2, R1-R3, X and L are disclosed herein. Also disclosed are compositions, methods of making and using compounds of the formula (I).