Patents by Inventor Nicholas D. Adams

Nicholas D. Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, methods and compositions
    Patent number: 7482343
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: January 27, 2009
    Assignees: Cytokinetics, Inc., SmithKline Beecham Corporation
    Inventors: Han-Jie Zhou, David J. Morgans, Jr., Gustave Bergnes, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Nicholas D. Adams
  • QUINAZOLINE DERIVATIVES AS P13 KINASE INHIBITORS
    Publication number: 20090018131
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinazoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinazoline derivatives.
    Type: Application
    Filed: June 12, 2008
    Publication date: January 15, 2009
    Inventors: Nicholas D. ADAMS, Joelle Lorraine BURGESS, Michael Gerard DARCY, Steven David KNIGHT, Kenneth Allen NEWLANDER, Lance H. RIDGERS, Stanley J. SCHMIDT
  • QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS
    Publication number: 20080300239
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
    Type: Application
    Filed: May 16, 2008
    Publication date: December 4, 2008
    Inventors: Nicholas D. Adams, Joelle Lorraine Burgess, Michael Gerrard Darcy, Carla A. Donatelli, Steven David Knight, Kenneth Allen Newlander, Lance Ridgers, Martha A. Sarpong, Stanley J. Schmidt
  • THIAZOLIDINEDIONE DERIVATIVES AS PI3 KINASE INHIBITORS
    Publication number: 20080255115
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using thiazolidinedione derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of thiazolidinedione derivatives.
    Type: Application
    Filed: August 24, 2007
    Publication date: October 16, 2008
    Inventors: Michael Gerard Darcy, Steven David Knight, Nicholas D. Adams, Stanley J. Schmidt
  • Certain chemical entities, compositions, and methods
    Publication number: 20080255182
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: January 7, 2008
    Publication date: October 16, 2008
    Inventors: Xiangping Qian, Andrew I. McDonald, Han-Jie Zhou, Luke W. Ashcraft, Bing Yao, Hong Jiang, Jennifer Kuo Chen Huang, Jianchao Wang, David J. Morgans, Bradley P. Morgan, Gustave Bergnes, Dashyant Dhanak, Steven D. Knight, Nicholas D. Adams, Cynthia A. Parrish, Kevin Duffy, Duke Fitch, Rosanna Tedesco
  • Compounds, Compositions, and Methods
    Publication number: 20080176830
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: April 13, 2006
    Publication date: July 24, 2008
    Inventors: Nicholas D. Adams, Michael Gerard Darcy, Dashyant Dhanak, Kevin J. Duffy, Duke M. Fitch, Steven David Knight, Kenneth Allen Newlander, Antony N. Shaw
  • Compounds, methods and compositions
    Patent number: 7166595
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: January 23, 2007
    Assignees: Cytokinetics, Inc., SmithKline Beecham Corporation
    Inventors: Han-Jie Zhou, David J. Morgans, Jr., Gustave Bergnes, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Nicholas D. Adams
  • Compounds, methods and compositions
    Publication number: 20040077662
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: May 2, 2003
    Publication date: April 22, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Han-Jie Zhou, David J. Morgans, Gustave Bergnes, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Nicholas D. Adams