Patents by Inventor Nicholas D. Andersen

Nicholas D. Andersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting smooth muscle cell migration and proliferation
    Patent number: 8119400
    Abstract: In particular embodiments, the present invention provides methods of inhibiting smooth muscle cell responses and methods of treating or preventing vascular proliferative disease caused by smooth muscle cell migration and proliferation. More specifically, smooth muscle cell responses are inhibited by introducing an agent into smooth muscle cells, wherein the agent inhibits an activity of one or more members of the myristoylated alanine-rich C kinase substrate (MARCKS) family of proteins. The invention also provides methods of inhibiting expression of one or more genes encoding a member of the MARCKS family of proteins in a cell.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: February 21, 2012
    Assignee: Beth Isreal Deaconess Medical Center, Inc.
    Inventors: Thomas S. Monahan, Frank W. LoGerfo, Nicholas D. Andersen
  • Methods of inhibiting smooth muscle cell migration and proliferation
    Publication number: 20080299654
    Abstract: In particular embodiments, the present invention provides methods of inhibiting smooth muscle cell responses and methods of treating or preventing vascular proliferative disease caused by smooth muscle cell migration and proliferation. More specifically, smooth muscle cell responses are inhibited by introducing an agent into smooth muscle cells, wherein the agent inhibits an activity of one or more members of the myristoylated alanine-rich C kinase substrate (MARCKS) family of proteins. The invention also provides methods of inhibiting expression of one or more genes encoding a member of the MARCKS family of proteins in a cell.
    Type: Application
    Filed: August 3, 2007
    Publication date: December 4, 2008
    Inventors: Thomas S. Monahan, Frank W. LoGerfo, Nicholas D. Andersen