Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.

Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.

Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.

Abstract: The present subject matter is directed to a method for treating a conscious. The method includes selecting a conscious patient having impaired cognitive function and applying electrical stimulation to at least a portion of the patient's intralaminar nuclei under conditions effective to relieve the patient's impaired cognitive function. A method for improving coordination of function across a patient's cortical regions is also described. The method includes applying electrical stimulation to two or more subdivisions of the patient's intralaminar nuclei. The two or more subdivisions of the patient's intralaminar nuclei modulate separate cortical regions. Using the methods of the present invention, patients suffering from impaired cognitive function can have at least a portion of the function restored, thus improving their quality of life and reducing societal costs.