Patents by Inventor Nicholas D. Tyrrell

Nicholas D. Tyrrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystallization process for preparing glycerophosphocholine
    Patent number: 5523450
    Abstract: A process for preparing substantially dry GPC (glycerophosphocholine in enantiomeric form) from wet GPC without racemisation, comprises subjecting the wet GPC to reduced pressure and elevated temperature, to reduce the water content and give highly viscous GPC; adding ethanol or another suitable solvent and crystallising GPC therefore with cooling; filtering the crystalline GPC and removing solvent therefrom under reduced pressure; characterised in that the elevated temperature is at least 45.degree. C.; and the solvent is added to the highly viscous GPC. This process produces an apparently new form of L-.alpha.-Glycerophosphocholine, m.p. 148.degree.-152.degree. C.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: June 4, 1996
    Assignee: Genzyme Limited
    Inventors: Christopher T. Evans, Raymond McCague, Nicholas D. Tyrrell