Patents by Inventor Nicholas David Lakin

Nicholas David Lakin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interactions of ATM, ATR or DAN-PK with p53
    Patent number: 7138236
    Abstract: The interaction of ATM and related protein kinases such as ATR and DNA-PK with p53 is disclosed, in particular the phosphorylation of Ser15 and Thr18 by these proteins. The activity of the proteins is shown to increase in the presence of DNA. Assays for modulators of phosphorylation by the interaction between the proteins and p53 or other proteins having similar phosphorylation sites are provided. Methods of purifying ATM or ATR employing DNA or NTA are also disclosed.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: November 21, 2006
    Assignee: Kudos Pharmaceuticals Limited
    Inventors: Stephen Philip Jackson, Nicholas David Lakin, Graeme Cameron Murray Smith