Patents by Inventor Nicholas FISCHER

Nicholas FISCHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12226529
    Abstract: Nanolipoprotein particles having at least a scaffold protein component and a membrane lipid component and related compositions, methods and systems are described. The membrane lipid component includes at least one or more membrane forming lipids, one or more polymerized lipids and/or one or more polymerizable lipids.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: February 18, 2025
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Craig D. Blanchette, Nicholas Fischer, Sean Fitzpatrick Gilmore, Amy Rasley, Paul Henderson
  • Publication number: 20240090359
    Abstract: A method may include detecting one or more objects within an agricultural environment based on an analysis of a first aerial image of the agricultural environment and determining a first navigational route for an autonomous tractor system to follow to perform an agricultural task within the agricultural environment in view of the detected objects. The autonomous tractor system may be configured to navigate through the agricultural environment via the first navigational route. The method may further include, while autonomous tractor system is navigating through the agricultural environment via the first navigational route, obtaining, from one or more sensors of the autonomous tractor system, data regarding a second object within an agricultural environment. The method may also include determining a second navigational route for the autonomous tractor system to follow to perform the agricultural task within the agricultural environment in view of the first navigational route and the second object.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 21, 2024
    Inventors: Timothy Bucher, Nicholas Fischer
  • Publication number: 20240069545
    Abstract: An example method may include obtaining operational instructions for operation of an autonomous tractor system to perform an agricultural task within an operational environment and directing the operational instructions to the autonomous tractor system. The method may also include while the autonomous tractor system is autonomously performing the agricultural task per the operational instructions, obtaining a notification that the autonomous tractor system is experiencing an unexpected event. The notification may provide an indication of the event and multiple responses performable by the autonomous tractor system in response to the event. In response to the notification, the method may include obtaining, based on input from a user, a selection of one of the multiple responses and directing the selected one of the multiple responses to the autonomous tractor system.
    Type: Application
    Filed: August 24, 2023
    Publication date: February 29, 2024
    Inventors: Timothy Bucher, Nicholas Fischer, David Chen
  • Publication number: 20230391223
    Abstract: An agricultural vehicle that includes a removable energy module configured to provide energy to power operations of the agricultural vehicle and a connection interface. The connection interface is configured to autonomous mechanically and electrically couple and decouple the removable energy module to the agricultural vehicle.
    Type: Application
    Filed: June 15, 2023
    Publication date: December 7, 2023
    Inventors: Timothy Bucher, Steven Holmes, Robert Culbertson, Harjot Bal, Aaron Leiba, Nicholas Fischer
  • Patent number: 11725170
    Abstract: The present disclosure relates to a biocompatible, in vitro probe system. The probe system may have a substrate and a culture well supported on the substrate. The culture well defines a three-dimensional volume for containing in vitro cultures of electroactive cells. The probe system has at least one probe subsystem supported on the substrate. The probe subsystem has at least one probe having an array of electrodes, with the probe being disposed within the culture well for in vitro electrically communicating with the electroactive cells. The probe subsystem is adapted to be interfaced to an external instrumentation/recording device.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: August 15, 2023
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: David Soscia, Heather Ann Enright, Nicholas Fischer, Doris Mailie Lam, Angela C. Tooker, Michael Triplett, Elizabeth K. Wheeler
  • Patent number: 11491215
    Abstract: Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: November 8, 2022
    Assignees: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, REGENTS OF THE UNIVERSITY OF NEW MEXICO
    Inventors: Nicholas Fischer, Amy Rasley, Terry Wu, Julie Lovchik
  • Publication number: 20220019213
    Abstract: Described herein is a delivery robot that can be programmed to travel from one location to another in open spaces that have few restrictions on the robot's path of travel. The delivery robot may operate in an autonomous mode, a remote controlled mode, or a combination thereof. The delivery robot can include a cargo area for transporting physical items. The robot can include exterior display devices and/or lighting devices to convey information to people that the robot may be encountering, including indications of the robot's direction of travel, current status, and/or other information.
    Type: Application
    Filed: December 9, 2019
    Publication date: January 20, 2022
    Inventors: Ali Haghighat Kashani, Colin Janssen, Ario Jafarzadeh, Bastian Lehmann, Sean Plaice, Dmitry Demeshchuk, Marc Greenberg, Kimia Nassehi, Nicholas Fischer, Chace Medeiros, Enger Bewza, Cormac Eubanks
  • Publication number: 20220005358
    Abstract: Techniques described in this application are directed to determining safe path navigation of an autonomous personal mobility device, including a self-driving electric scooter, using sensors and/or data from other sources. The autonomous personal mobility device is configured to generate maps and transform the maps into tile segments that can be shared with other autonomous personal mobility devices. Techniques further include receiving a request for an autonomous personal mobility device at a location, and enabling the autonomous personal mobility device to self-drive to the location.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 6, 2022
    Inventors: Ali Haghighat Kashani, Bastian Jan Michael Lehmann, Sean Tracey Plaice, Nicholas Fischer
  • Publication number: 20210139828
    Abstract: The present disclosure relates to a biocompatible, in vitro probe system. The probe system may have a substrate and a culture well supported on the substrate. The culture well defines a three-dimensional volume for containing in vitro cultures of electroactive cells. The probe system has at least one probe subsystem supported on the substrate. The probe subsystem has at least one probe having an array of electrodes, with the probe being disposed within the culture well for in vitro electrically communicating with the electroactive cells. The probe subsystem is adapted to be interfaced to an external instrumentation/recording device.
    Type: Application
    Filed: November 7, 2019
    Publication date: May 13, 2021
    Inventors: David SOSCIA, Heather Ann ENRIGHT, Nicholas FISCHER, Doris Mailie LAM, Angela C. TOOKER, Michael TRIPLETT, Elizabeth K. WHEELER
  • Publication number: 20200108133
    Abstract: Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
    Type: Application
    Filed: August 16, 2019
    Publication date: April 9, 2020
    Inventors: Nicholas Fischer, Amy Rasley, Terry Wu, Julie Lovchik
  • Publication number: 20190307692
    Abstract: Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more lysoplipids.
    Type: Application
    Filed: March 3, 2017
    Publication date: October 10, 2019
    Inventors: Craig D. BLANCHETTE, Nicholas FISCHER, Sean Fitzpatrick GILMORE, Paul HENDERSON
  • Publication number: 20190142752
    Abstract: Nanolipoprotein particles having at least a scaffold protein component and a membrane lipid component and related compositions, methods and systems are described. The membrane lipid component includes at least one or more membrane forming lipids, one or more polymerized lipids and/or one or more polymerizable lipids.
    Type: Application
    Filed: August 25, 2016
    Publication date: May 16, 2019
    Inventors: Craig D. BLANCHETTE, Nicholas FISCHER, Sean Fitzpatrick GILMORE, Amy RASLEY, Paul HENDERSON