Patents by Inventor Nicholas G. Sapiezynski

Nicholas G. Sapiezynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Catalytic C—H bond activation
    Patent number: 9416080
    Abstract: Disclosed is a method for the transition metal-mediated oxidation of C—H bonds to form C—O or C—S bonds. The methods are useful for the formation of ethers (R—OR?) from alcohols, R?OH, and sp3-hybridized C—H bonds in substrates, R—H. Aryl or heteroaryl acetates may also be used for C—H to C—OAr bond formation. The methods are also useful in the preparation of C—S bonds from acetyl-protected thiols, MeC(O)SR, and disulfides, RSSR. Advantageously, the methods minimize reaction steps, the handling of oxidized intermediates, and environmental impact.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: August 16, 2016
    Assignee: Georgetown University
    Inventors: Timothy H. Warren, Nicholas G. Sapiezynski
  • Catalytic C-H Bond Activation
    Publication number: 20150321982
    Abstract: Disclosed is a method for the transition metal-mediated oxidation of C—H bonds to form C—O or C—S bonds. The methods are useful for the formation of ethers (R—OR?) from alcohols, R?OH, and sp3-hybridized C—H bonds in substrates, R—H. Aryl or heteroaryl acetates may also be used for C—H to C-OAr bond formation. The methods are also useful in the preparation of C—S bonds from acetyl-protected thiols, MeC(O)SR, and disulfides, RSSR. Advantageously, the methods minimize reaction steps, the handling of oxidized intermediates, and environmental impact.
    Type: Application
    Filed: June 14, 2013
    Publication date: November 12, 2015
    Inventors: Timothy H. Warren, Nicholas G. Sapiezynski