Abstract: Disclosed is a method of adapting the operation of an implantable device for delivering neurostimulation therapy to a patient. The method comprises: delivering the neurostimulation therapy to electrically excitable tissue of the patient according to at least one therapy parameter; measuring a physiological characteristic of the patient; adjusting the at least one therapy parameter according to a schedule of adjustment and the measured physiological characteristic; and repeating the delivering, measuring, and adjusting.

Abstract: A vehicle seating assembly includes a seat and a seatback. The seatback includes a frame that has opposing first and second frame members and first and second displaceable panels that are pivotably coupled to the first and second frame members. The first and second displaceable panels are movable between stored positions and deployed positions in response to a force exerted on the seatback.

Abstract: Disclosed is an automated programming system for a neuromodulation device that is configured to assist a clinician to efficiently program the neuromodulation device for a particular patient. In particular, the assisted programming system comprises a stimulation user interface control that is configured to cause the intensity of the neural stimulus to ramp up with time as long as the patient continues to interact with the control. The value of stimulus intensity at which the patient ceases to interact with the control is recorded as a significant perceptual marker upon which subsequent steps in the assisted programming workflow are based. This user interface design takes advantage of the human withdrawal reflex, whereby the patient is likely to instinctively release the button upon receiving uncomfortable stimulation. The design therefore minimises the training burden placed on the patient in using the assisted programming system.

Abstract: Disclosed is an assisted programming system for a neuromodulation device that is configured to assist a clinician to efficiently program the neuromodulation device for a particular patient. In particular, the assisted programming system comprises a processor configured to ramp a stimulus intensity parameter to or from a predetermined target intensity while the neural stimuli are delivered by the device according to the ramping value of the stimulus intensity parameter. The ramp traverses stimulus intensities below a predetermined threshold at a faster rate than stimulus intensities above the predetermined threshold. The effect is to improve the apparent responsiveness of the neuromodulation device by reducing the amount of time spent traversing stimulus intensities below a perception threshold, while avoiding a sensation of abruptness.

Abstract: A vehicle seating assembly includes a seat and a seatback. The seatback includes a frame that has opposing first and second frame members and first and second displaceable panels that are pivotably coupled to the first and second frame members. The first and second displaceable panels are movable between stored positions and deployed positions in response to a force exerted on the seatback.

Abstract: Disclosed is an assisted programming system for a neuromodulation device that is configured to assist a clinician to efficiently program the neuromodulation device for a particular patient. In particular, the assisted programming system comprises a processor configured to predict physiological thresholds of a particular stimulus electrode configuration from perceptual markers obtained using patient reported responses to neural stimuli via that stimulus electrode configuration. Alternatively, the processor may be configured to predict perceptual markers of a particular stimulus electrode configuration from physiological thresholds obtained using measured neural responses to neural stimuli delivered via that stimulus electrode configuration.

Abstract: Disclosed is an assisted programming system for a neuromodulation device that is configured to assist a clinician to efficiently program the neuromodulation device for a particular patient. In particular, the assisted programming system comprises a user interface with a plurality of controls such as switches, each switch control corresponding to a predetermined configuration of the stimulus electrodes. Activation and de-activation of the switch controls causes stimuli to be delivered via the respective stimulus electrode configurations. Alternatively, or additionally, the user interface controls may be tiles, whose activation may cause the state of delivery of stimulation via the respective stimulus electrode configurations to be inverted.

Abstract: Disclosed are methods and devices for analysing signal windows captured subsequent to delivered neural stimuli and for providing a quality score for each signal window. The quality score is indicative of how closely the captured signal window resembles, or how likely that the captured signal window contains, an ECAP. The quality score may be provided to a process supervising a feedback loop of the closed-loop neural stimulation device delivering the stimuli and capturing the signal windows to ensure the delivered stimuli are appropriate. For example, if the score falls below a predetermined threshold, the supervisor may take a mitigation action to prevent inappropriate adjustment to the intensity of the delivered stimuli by the feedback loop, such as suspending operation of the feedback loop.

Abstract: A neuromodulation system and method. An implantable electrode array comprises a plurality of electrodes. A stimulus source provides neural stimuli delivered via stimulus electrodes to neural tissue to evoke neural responses. Measurement circuitry captures signal windows sensed from the neural tissue subsequent to each stimulus. A control unit controls the neural stimuli according to a stimulus intensity parameter. A processor introduces a perturbation to the parameter from a baseline stimulus intensity. A time series of intensities of the evoked neural responses is obtained. from which a time series of estimates of at least one physiological characteristic of the neural tissue is obtained. Each physiological characteristic being variable as a result of a posture wave. A baseline value of each physiological characteristic is estimated from the time series of estimates of each physiological characteristic.

Abstract: A vehicle seating assembly includes a seat and a seatback. The seatback includes a frame that has opposing first and second frame members and first and second displaceable panels that are pivotably coupled to the first and second frame members. The first and second displaceable panels are movable between stored positions and deployed positions in response to a force exerted on the seatback.

Abstract: Disclosed is a neurostimulation system comprising: a neuromodulation device for controllably delivering neural stimuli; a headset configured to be worn by the patient and to display images of a virtual object to the patient; one or more sensors configured to perceive a gesture of the patient; and an external computing device. The neuromodulation device comprises: a plurality of implantable electrodes; a stimulus source configured to deliver neural stimuli via selected ones of the implantable electrodes to a neural pathway of a patient; and a control unit configured to control the stimulus source to deliver each neural stimulus according to one or more stimulus parameters. The external computing device comprises a processor in communication with the neuromodulation device, the headset, and the one or more sensors.

Abstract: An implantable device comprising: stimulus electrodes and measurement electrodes; a stimulus source to provide a neural stimulus to be delivered to a neural pathway of a patient to evoke a neural response; measurement circuitry configured to capture a signal window sensed on the neural pathway; and a control unit configured to implement closed-loop neurostimulation therapy by: controlling the stimulus source to provide the neural stimulus according to a stimulus intensity parameter; measuring a characteristic of the signal window; computing a feedback variable from an intensity of an evoked neural response in the signal window; adjusting the stimulus intensity parameter using the feedback variable; and repeating the controlling, measuring, computing, and adjusting to maintain the feedback variable at a target, thereby obtaining multiple measured intensities of neural responses; and computing one or more quantitative indicators of efficacy of the closed-loop neurostimulation therapy using the measured characte

Abstract: A vehicle seating assembly includes a seat and a seatback. The seatback includes a frame that has opposing first and second frame members and first and second displaceable panels that are pivotably coupled to the first and second frame members. The first and second displaceable panels are movable between stored positions and deployed positions in response to a force exerted on the seatback.

Abstract: There is provided a method and implantable device for controlling a neural stimulus, the neural stimulus being defined by an artefact mitigation status. The method comprises generating a first neural stimulus for delivery to neural tissue, sensing a first signal subsequent to the first neural stimulus, generating a second neural stimulus for delivery to the neural tissue, and sensing a second signal subsequent to the second neural stimulus. The method further comprises determining an artefact mitigation measure (AMM) effect level based on the first sensed signal and the second sensed signal, and setting, in response to comparing the AMM effect level with an AMM effect threshold, the artefact mitigation status of a third neural stimulus to active.

Abstract: An implantable device for delivering closed-loop neural stimulation therapy. The device comprises: a plurality of electrodes; a stimulus source to provide neural stimuli via the electrodes to a neural pathway; measurement circuitry to process signals sensed at the electrodes; and a control unit. The control unit is configured to: control the stimulus source to provide a first neural stimulus according to a first stimulus parameter; measure an intensity of a neural response evoked by the first stimulus; compute a feedback variable from the neural response; adjust the first stimulus parameter; repeat the control, measure, compute and adjust to maintain the feedback variable at a target response intensity; control the stimulus source to provide, interleaved with the first neural stimuli, a plurality of second neural stimuli according to respective second stimulus parameters; and monitor the therapy by analysing the sensed signals subsequent to each second neural stimulus.

Abstract: Disclosed is a neuromodulation system comprising a neuromodulation device for controllably delivering a neural stimulus, and a processor.

Abstract: Disclosed is an implantable device for lead offset determination, comprising first and second electrode leads. A stimulus is delivered from one lead to tissue, and a signal is sensed from the tissue by the other lead. The sensed signal is processed to produce a measure of a stimulus artefact present in the signal. The stimulus artefact measure is used to produce a measure of an offset between the first electrode lead and the second electrode lead, such as by applying a distance-squared. analytical model to measures of stimulus artefact obtained from at least two sense electrodes. And/or, a compound action potential evoked by the stimulus is sensed from neural tissue, a latency of the evoked compound action potential is measured, and a measure of an offset between the first electrode lead and the second electrode lead is produced from the latency.

Abstract: A vehicle seating assembly includes a seat and a seatback. The seatback includes a frame that has opposing first and second frame members and first and second displaceable panels that are pivotably coupled to the first and second frame members. The first and second displaceable panels are movable between stored positions and deployed positions in response to a force exerted on the seatback.

Abstract: Disclosed is a method of adapting the operation of an implantable device for delivering neurostimulation therapy to a patient. The method comprises: delivering the neurostimulation therapy to electrically excitable tissue of the patient according to at least one therapy parameter; measuring a physiological characteristic of the patient; adjusting the at least one therapy parameter according to a schedule of adjustment and the measured physiological characteristic; and repeating the delivering, measuring, and adjusting.

Abstract: An apparatus supplying alternating current to a load.