Patents by Inventor Nicholas J. Manesis

Nicholas J. Manesis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE
    Publication number: 20240034853
    Abstract: Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
    Type: Application
    Filed: June 27, 2023
    Publication date: February 1, 2024
    Inventors: Nicholas J. MANESIS, Dylan B. HOLLRIGEL
  • Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
    Patent number: 11833269
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: December 5, 2023
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Nicholas J. Manesis, Jacob Pollock
  • DERMAL FILLER COMPOSITIONS INCLUDING ANTIOXIDANTS
    Publication number: 20230310700
    Abstract: Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins.
    Type: Application
    Filed: November 11, 2022
    Publication date: October 5, 2023
    Inventors: Futian Liu, Xiaojie Yu, Nicholas J. Manesis, Athene Wan Chie Chan
  • Biocompatible porous materials and methods of manufacture and use
    Patent number: 11692075
    Abstract: Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: July 4, 2023
    Assignee: Poragen LLC
    Inventors: Nicholas J. Manesis, Dylan B. Hollrigel
  • CROSS LINKED SILK-HYALURONIC ACID COMPOSITION
    Publication number: 20220370323
    Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
    Type: Application
    Filed: April 4, 2022
    Publication date: November 24, 2022
    Inventors: Elizabeta PAVLOVIC, Monica A. SERBAN, Xiaojie YU, Nicholas J. MANESIS
  • CORNEAL INLAY DESIGN AND METHODS OF CORRECTING VISION
    Publication number: 20220273422
    Abstract: A corneal inlay device comprising a flat or flat-like base and a dome or droplet top. The corneal inlay can be used to treat, for example without limitation, presbyopia, while reducing or eliminating the risk of a patient developing corneal haze.
    Type: Application
    Filed: July 30, 2020
    Publication date: September 1, 2022
    Inventors: Nicholas J. Manesis, Phihoa Tran-Hata, Alan Le, Khanh Nguyen
  • BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE
    Publication number: 20220033611
    Abstract: Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
    Type: Application
    Filed: October 19, 2021
    Publication date: February 3, 2022
    Inventors: Nicholas J. MANESIS, Dylan B. HOLLRIGEL
  • DERMAL FILLER COMPOSITIONS
    Publication number: 20220023186
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.
    Type: Application
    Filed: August 6, 2021
    Publication date: January 27, 2022
    Inventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Nicholas J. Manesis
  • Porogen compositions, methods of making and uses
    Patent number: 11202853
    Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: December 21, 2021
    Assignee: Allergan, Inc.
    Inventors: Futian Liu, Nicholas J Manesis, Xiaojie Yu, Athene W. Chan
  • CORNEAL DEVICE POSITIONING SYSTEMS, DEVICES, AND METHODS
    Publication number: 20210322149
    Abstract: Devices and systems adapted for at least one of storing a corneal device and positioning a corneal device onto target tissue.
    Type: Application
    Filed: June 22, 2018
    Publication date: October 21, 2021
    Inventors: Niclas Henning ZIEGER, Nicholas J. MANESIS, Nicolas ESGUERRA, Rachel Marie WONG
  • Biocompatible porous materials and methods of manufacture and use
    Patent number: 11149127
    Abstract: Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: October 19, 2021
    Assignee: Poragen LLC
    Inventors: Nicholas J. Manesis, Dylan B. Hollrigel
  • BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE
    Publication number: 20210301098
    Abstract: Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Inventors: Nicholas J. MANESIS, Dylan B. HOLLRIGEL
  • Dermal filler compositions
    Patent number: 11083684
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: August 10, 2021
    Assignee: ALLERGAN INDUSTRIE, SAS
    Inventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Nicholas J. Manesis
  • Dermal filler compositions including antioxidants
    Patent number: 11000626
    Abstract: Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: May 11, 2021
    Assignee: ALLERGAN INDUSTRIE, SAS
    Inventors: Futian Liu, Xiaojie Yu, Jessamine P. Winer-Jones, Nicholas J. Manesis, Hengli Liu, Gabriel Njikang, Athene Wan Chie Chan
  • Dermal filler compositions for fine line treatment
    Patent number: 10994049
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: May 4, 2021
    Assignee: ALLERGAN INDUSTRIE, SAS
    Inventors: Gabriel N. Njikang, Xiaojie Yu, Futian Liu, Sumit Paliwal, Nicholas J. Manesis
  • DERMAL FILLER COMPOSITIONS INCLUDING ANTIOXIDANTS
    Publication number: 20210023265
    Abstract: Dermal filler compositions can comprise hyaluronic acid and a conjugated vitamin C derivative. The compositions can provide for extended release of active vitamin C into tissue, which can promote collagenesis and other benefits to skin.
    Type: Application
    Filed: October 13, 2020
    Publication date: January 28, 2021
    Inventors: Futian LIU, Xiaojie YU, Jessamine P. WINER-JONES, Nicholas J. MANESIS, Hengli LIU, Gabriel NJIKANG, Athene Wan Chie CHAN
  • DERMAL FILLER COMPOSITIONS FOR FINE LINE TREATMENT
    Publication number: 20200353124
    Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: Gabriel N. NJIKANG, Xiaojie YU, Futian LIU, Sumit PALIWAL, Nicholas J. MANESIS
  • CROSS LINKED SILK-HYALURONIC ACID COMPOSITION
    Publication number: 20200352843
    Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: Elizabeta PAVLOVIC, Monica A. SERBAN, Xiaojie YU, Nicholas J. MANESIS
  • Cross linked silk-hyaluronic acid composition
    Patent number: 10758470
    Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 1, 2020
    Assignee: ALLERGAN, INC.
    Inventors: Elizabeta Pavlovic, Monica A. Serban, Xiaojie Yu, Nicholas J. Manesis
  • POROGEN COMPOSITIONS, METHODS OF MAKING AND USES
    Publication number: 20200237968
    Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.
    Type: Application
    Filed: April 16, 2020
    Publication date: July 30, 2020
    Inventors: Futian Liu, Nicholas J. Manesis, Xiaojie Yu, Athene W. Chan