Patents by Inventor Nicholas J. Virca

Nicholas J. Virca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of prostate cancer using hedgehog pathway inhibitors
    Patent number: 10363252
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: July 30, 2019
    Assignee: HEDGEPATH PHARMACEUTICALS, INC.
    Inventors: Nicholas J. Virca, Francis E. O'Donnell, Jr.
  • Treatment of lung cancer using hedgehog pathway inhibitors
    Patent number: 10328072
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: June 25, 2019
    Assignee: HEDGEPATH PHARMACEUTICALS, INC.
    Inventors: Nicholas J. Virca, Francis E. O'Donnell, Jr.
  • Treatment and prognostic monitoring of non-cancerous proliferation disorders using hedgehog pathway inhibitors
    Patent number: 9968600
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: May 15, 2018
    Assignee: HEDGEPATH PHARMACEUTICALS, INC.
    Inventors: Nicholas J. Virca, Francis E. O'Donnell, Jr.
  • Treatment and prognostic monitoring of cancerous proliferation disorders using Hedgehog pathway inhibitors
    Patent number: 9962381
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: May 8, 2018
    Assignee: HEDGEPATH PHARMACEUTICALS, INC.
    Inventors: Nicholas J. Virca, Francis E. O'Donnell, Jr.
  • TREATMENT AND PROGNOSTIC MONITORING OF PROLIFERATION DISORDERS USING HEDGEHOG PATHWAY INHIBITORS
    Publication number: 20160074393
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Application
    Filed: November 20, 2015
    Publication date: March 17, 2016
    Inventors: Nicholas J. VIRCA, Francis E. O'DONNELL, JR.
  • Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors
    Patent number: 9192609
    Abstract: The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers, using an inhibitor of the Hedgehog pathway (HhP); and methods for monitoring subjects undergoing such treatments based on biomarkers and other criteria predictive of efficacy.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: November 24, 2015
    Assignee: HEDGEPATH PHARMACEUTICALS, INC.
    Inventors: Nicholas J. Virca, Francis E. O'Donnell, Jr.
  • Vial cap coupling device
    Patent number: 4753358
    Abstract: A vial cap coupling device for flexibly coupling together a vial and its sealing cap includes a cylindrical retainer having an inner surface which forms a cavity for snugly receiving the sealing cap and firmly engaging an outer surface of the cap, a slide ring which has an inner diameter which is about the same as the outside diameter of the cylindrical portion of the vial so that the slide ring can be slid up the cylindrical portion of the vial to the rim at the upper end of the cylindrical portion, and a hinge which at its ends is integrally connected to the retainer and slide ring. The vial cap coupling device retainer further includes a small resilient flange which has an upward shelf which retains within the cavity a sealing cap by abutting against a bottom of the cap.
    Type: Grant
    Filed: March 2, 1987
    Date of Patent: June 28, 1988
    Assignee: Promega Corporation
    Inventors: Nicholas J. Virca, Kenneth Muderlak