Patents by Inventor Nicholas J. Westwood

Nicholas J. Westwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of anti-protozoal agents
    Patent number: 7067315
    Abstract: The present invention provides novel assay systems and methods for monitoring cell invasion by protozoal parasites. The present invention further provides methods of using these assays systems to identify compounds that treat or prevent protozoal infection. The present invention further provides pharmaceutical compositions that have anit-protozoal activity and methods of treating infections.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: June 27, 2006
    Assignees: President and Fellows of Harvard College, University of Vermont
    Inventors: Nicholas J. Westwood, Gary E. Ward, Kimberly L. Carey, Timothy J. Mitchinson
  • Identification of anti-protozoal agents
    Publication number: 20030113822
    Abstract: The present invention provides novel assay systems and methods for monitoring cell invasion by protozoal parasites. The present invention further provides methods of using these assays systems to identify compounds that treat or prevent protozoal infection. The present invention further provides pharmaceutical compositions that have anit-protozoal activity and methods of treating infections.
    Type: Application
    Filed: May 22, 2002
    Publication date: June 19, 2003
    Applicant: President and Fellows of Harvard College for Inventors Westwood and Mitchison
    Inventors: Nicholas J. Westwood, Gary E. Ward, Kimberly L. Carey, Timothy J. Mitchinson
  • Biomimetic combinatorial synthesis
    Publication number: 20010024798
    Abstract: The present invention provides biomimetic compounds and libraries thereof, as well as methods for their production. In general, the inventive method involves the selection of a desired biological synthetic pathway and mimics that synthetic pathway utilizing modern synthetic tools. The structures formed from this method are preferably generated in fewer than four steps. These scaffold structures can then be functionalized to yield biomimetic compounds and libraries of compounds. In preferred embodiments, biomimetic compounds and libraries are generated from an oxidative phenolic coupling reaction. In other particularly preferred embodiments, the compounds and libraries of compounds are generated from cascade reactions to yield bicyclo [n.3.1] ring systems, medium ring systems, and fused ring systems.
    Type: Application
    Filed: April 19, 2001
    Publication date: September 27, 2001
    Inventors: Matthew D. Shair, Craig W. Lindsley, Henry E. Pelish, Scott M. Sheehan, Brian C. Goess, Mark E. Layton, Lawrence K. Chan, Chuo Chen, Nicholas J. Westwood