Patents by Inventor Nicholas Jack Heredia

Nicholas Jack Heredia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANALYSIS OF NUCLEIC ACIDS
    Publication number: 20230287486
    Abstract: Method of haplotype analysis. In an exemplary method, an aqueous phase containing nucleic acid may be partitioned into a plurality of discrete volumes. At least one allele sequence may be amplified in the volumes from each of a first polymorphic locus and a second polymorphic locus that exhibit sequence variation in the nucleic acid. At least one measure of co-amplification of allele sequences from both loci in the same volumes may be determined. A haplotype of the first and second loci may be selected based on the at least one measure of co-amplification.
    Type: Application
    Filed: November 14, 2022
    Publication date: September 14, 2023
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: John F. REGAN, Serge SAXONOV, Michael Y. LUCERO, Benjamin J. HINDSON, Phillip BELGRADER, Simant DUBE, Austin SO, Jeffrey Clark MELLEN, Nicholas Jack HEREDIA, Kevin D. NESS, Billy W. COLSTON, Jr.
  • Methods and compositions for using oils for analysis and detection of molecules
    Patent number: 9427737
    Abstract: Oil compositions and methods for use in droplet formation or in spacing of droplets are disclosed. The oil compositions may include a combination, such as a silicone oil and a fluorine-containing compound. The droplets can contain analytes (e.g., nucleic acids) and may be used for molecular reactions (e.g., digital PCR) and detection.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: August 30, 2016
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Nicholas Jack Heredia, Anthony J. Makarewicz, Jr.
  • Analysis of nucleic acids
    Patent number: 9127312
    Abstract: Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g., whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: September 8, 2015
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: John Frederick Regan, Serge Saxonov, Mike Lucero, Ben Hindson, Phil Belgrader, Simant Dube, Austin So, Jeffrey Clark Mellen, Nicholas Jack Heredia, Kevin Ness, Bill Colston
  • METHODS AND COMPOSITIONS FOR USING OILS FOR ANALYSIS AND DETECTION OF MOLECULES
    Publication number: 20140170736
    Abstract: Oil compositions and methods for use in droplet formation or in spacing of droplets are disclosed. The oil compositions may include a combination, such as a silicone oil and a fluorine-containing compound. The droplets can contain analytes (e.g., nucleic acids) and may be used for molecular reactions (e.g., digital PCR) and detection.
    Type: Application
    Filed: December 12, 2013
    Publication date: June 19, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Nicholas Jack Heredia, Anthony J. Makarewicz, JR.
  • Analysis of nucleic acids
    Publication number: 20120322058
    Abstract: Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g., whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
    Type: Application
    Filed: February 9, 2012
    Publication date: December 20, 2012
    Applicant: Bio-Rad Laboratories
    Inventors: John Frederick Regan, Serge Saxonov, Mike Lucero, Ben Hindson, Phil Belgrader, Simant Dube, Austin So, Jeffrey Clark Mellen, Nicholas Jack Heredia, Kevin Ness, Bill Colston
  • METHODS AND SYSTEMS FOR INTRODUCING FUNCTIONAL POLYNUCLEOTIDES INTO A TARGET POLYNUCLEOTIDE
    Publication number: 20100298170
    Abstract: A method and system is presented for introducing functional polynucleotides into a target polynucleotide using transposons.
    Type: Application
    Filed: May 12, 2010
    Publication date: November 25, 2010
    Inventors: Nicholas Jack Heredia, Christine Akiko Hara, N. Reginald Beer