Abstract: An airfoil for a turbine engine having a spar assembly. The spar assembly including a composite spar, a metallic hub, and a composite body. The metallic hub can receive a portion of the composite spar at an interior surface to define an overlapping region. The composite body is located at the overlapping region.

Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.

Abstract: A medical device, including an implantable portion of the medical device, the implantable portion including at least one electrode, wherein the implantable portion is configured to, while implanted in a human, obtain data indicative of wear of the at least one electrode. In an exemplary embodiment, the medical device is a cochlear implant.

Abstract: The present disclosure relates to an airfoil assembly for a turbine engine and methods of assembly thereof. The airfoil assembly generally includes a composite airfoil and a spar. The composite airfoil has a pressure side and a suction side extending in an axial direction between a leading edge and a trailing edge defining a chordwise direction and extending radially between a root and a tip defining a spanwise direction and having a span-length. The spar includes a first portion including a first material and a second portion joined at an interface with the first portion. The second portion further includes a second material, different from the first material, joined to the first portion at an interface. The method generally includes joining the first portion with the second portion at the interface; and assembling the spar with the composite airfoil.

Abstract: Presenting first drawer area on a first display device in an instrument panel of a vehicle, the first drawer area presented in an extended state; presenting second drawer area on a second display device in the instrument panel of the vehicle, the second drawer area presented in a retracted state; receiving first transition command regarding the first and second drawer areas; and in response to receiving the first transition command: presenting the first drawer area in the retracted state on the first display device, wherein the first content is not visible in the first drawer area in the retracted state; and presenting the second drawer area in the extended state on the second display device, wherein the first content of the first application is visible in the second drawer area.

Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latching assembly may comprise a latch body, a locking member, a biasing member, and an activating member. Additional features of the container may include handles and strength increasing features. The base and lid may also feature attachment points for various accessories. A carry strap may attach to the base of the container to allow a user to lift and carry the container. The container may also have a wheels attached to the bottom portion and/or across the bottom portion to one side of the sidewall structure. In addition, in exemplary containers with wheels, a pull handle may be attached to a side opposite the wheels. The lid may include a lid support member that can act as a molle board to releasably secure items to the lid support member while also providing structural support to the lid.

Abstract: The disclosure features macrocyclic compounds, alone and in combination with other therapeutic agents, as well as pharmaceutical compositions and protein complexes thereof, capable of modulating biological processes including RAS and RAS-RAF inhibition, and their uses in the treatment of cancers.

Abstract: A method of controlling a chemical reaction is disclosed. The method may include feeding a solution at a first flow rate into a reactor and detecting a sound in the reactor using a sound sensor that is adjacent to the reactor. The sound sensor may convert the sound into a sound signal. After the sound signal is acquired, it is compared to a stored sound signal or a stored sound threshold to detect a reaction event. The method may include adjusting the flow rate of solutions into the reactor in response to the reaction event.

Abstract: Methods, devices and systems are disclosed for inter-app communications between software applications on a mobile communications device. In one aspect, a computer-readable medium on a mobile computing device comprising an inter-application communication data structure to facilitate transitioning and distributing data between software applications in a shared app group for an operating system of the mobile computing device includes a scheme field of the data structure providing a scheme id associated with a target software app to transition to from a source software app, wherein the scheme id is listed on a scheme list stored with the source software app; and a payload field of the data structure providing data and/or an identification where to access data in a shared file system accessible to the software applications in the shared app group, wherein the payload field is encrypted.

Abstract: A gas turbine engine including: a turbomachine having a compressor section, a combustion section, and a turbine section arranged in serial flow order; a fan defining a fan axis and comprising a plurality of fan blades rotatable about the fan axis; and a pitch change mechanism operable with the plurality of fan blades, the pitch change mechanism including a plurality of linkages, the plurality of linkages including a first linkage coupled to a first fan blade of the plurality of fan blades and a second linkage coupled to a second fan blade of the plurality of fan blades; and a non-uniform blade actuator system operable with one or more of the plurality of linkages to control a pitch of the first fan blade relative to a pitch of the second fan blade.

Abstract: A gas turbine engine includes a turbomachine comprising a compressor section, a combustion section, and a turbine section arranged in serial flow order. A fan defining a fan axis and comprising a plurality of fan blades is rotatable about the fan axis. A pitch change mechanism is operable with the plurality of fan blades to control a pitch of the plurality of fan blades. A counterweight is connected to each respective fan blade. A spring mechanism is operably associated with each fan blade of the plurality of fan blades to create a spring twisting moment on the respective fan blade that is counter to a centrifugal twisting moment of the respective fan blade.

Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: A rotor assembly is provided, along with gas turbine engines for its use. The rotor assembly may include a spool defining a plurality of apertures arranged in a first row and spaced circumferentially around the spool, wherein each aperture of the plurality of apertures extends through the spool from a radially inward-facing surface to a radially outward-facing surface; and a blade assembly comprising at least two blades connected to each other via a platform, wherein each blade extends through a respective aperture.

Abstract: A joint for connecting a center wing box to a bulkhead of an aircraft. The joint includes a flex angle member with a first section shaped to abut against and be connected to the center wing box, a second section shaped to abut against and be connected to a first side of the deck of the bulkhead, and an intermediate rounded corner positioned between the first and second sections. First support members are attached to the center wing box at first pins and support a first side of the second section of the flex angle member. Second support members are attached to the web of the bulkhead at second pins and support a second side of the second section of the flex angle member. The first support members are positioned on a first side of the deck of the bulkhead and the second support members are positioned on an opposing second side of the deck.

Abstract: Systems and methods for digital property protection are disclosed. For example, indication may be received that an entity has applied for an insurance policy to insure against theft of digital property. The digital property may be registered and a valuation of the digital property may be generated. Due diligence processes may be performed, including assessment of physical and/or network security mechanisms to prevent theft of the digital property. A recommendation to issue the insurance policy may be generated and sent in examples where the due diligence processes return favorable results. Terms generation and/or identification may be performed, and claims processing based at least in part on loss matrixes may also be performed.

Abstract: Systems and methods for intellectual property (IP) asset protection are disclosed. For example, by analyzing characteristic information associated with a user, along with feedback from one or more potential insurers, the system may determine various terms of an insurance policy for protecting the user against claims of IP infringement. The policy may provide for financial reimbursement for costs incurred while taking active measures to mitigate losses and/or defend against such claims. In addition, the system may analyze the characteristic information to identify various users having a low exposure of an infringement claim being asserted. The identified users may be actively targeted to acquire an IP protection policy.

Abstract: A composite airfoil having a non-metallic leading edge protective wrap is provided. In one aspect, the airfoil has a composite core having a pressure sidewall and a suction sidewall each extending between a core leading edge and a core trailing edge. A leading edge protective wrap protects the core leading edge and includes a trailing wrap and a leading wrap. The trailing wrap wraps around the core leading edge and is connected to the composite core. The leading wrap wraps around the core leading edge and is connected to the trailing wrap. The trailing and leading wraps both have leading edges that are spaced from one another. A filler is positioned between the leading edges of the trailing and leading wraps. A protective nose is connected to the leading edge of the leading wrap. The components of the leading edge protective wrap are formed of non-metallic materials.

Abstract: Methods and apparatus consistent with the invention provide the ability to organize, index, search, and present time series data based on searches. Time series data are sequences of time stamped records occurring in one or more usually continuous streams, representing some type of activity. In one embodiment, time series data is stored as discrete events time stamps. A search is received and relevant event information is retrieved based in whole or in part on the time stamp, a keyword indexing mechanism, or statistical indices calculated at the time of the search.

Abstract: An infant positioner and an entertainment component that is useable with the infant positioner in different positions. The entertainment component can be placed in at least a first position and a second position different from the first position. The entertainment component is coupled to a support structure of the infant positioner while the entertainment component is in the first position as well as in the second position.

Abstract: An infant positioner and an entertainment component that is useable with the infant positioner in different positions. The entertainment component can be placed in at least a first position and a second position different from the first position. The entertainment component is coupled to a support structure of the infant positioner while the entertainment component is in the first position as well as in the second position.