Patents by Inventor Nicholas Leiva

Nicholas Leiva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphate limited inducible promoter and a expression system
    Patent number: 8415120
    Abstract: An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: April 9, 2013
    Assignee: Danisco US Inc.
    Inventors: Katherine D. Collier, Edwin Lee, Nicholas Leiva, Thomas B. Morrison, Volker Schellenberger, Olga V. Selifonova, Adam C. Kean
  • Acetolactate synthase (ALS) selectable marker from
    Patent number: 8138321
    Abstract: A nucleic acid encoding an acetolactate synthase (ALS) protein that provides resistance to ALS inhibitors, e.g., sulphonylurea and imidazolinone compounds, is provided. The nucleic acid may be used as a selectable marker for expression of a protein of interest in host cells.
    Type: Grant
    Filed: September 21, 2007
    Date of Patent: March 20, 2012
    Assignee: Danisco US Inc.
    Inventors: Benjamin S. Bower, Nigel Dunn-Coleman, Nicholas Leiva
  • Phosphate Limited Inducible Promoter and A Bacillus Expression System
    Publication number: 20110262953
    Abstract: An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins.
    Type: Application
    Filed: November 19, 2010
    Publication date: October 27, 2011
    Applicant: Danisco US Inc.
    Inventors: Katherine D. Collier, Edwin Lee, Nicholas Leiva, Thomas B. Morrison, Volker Schellenberger, Olga V. Selifonova, Adam C. Kean
  • Phosphate limited inducible promoter and a expression system
    Patent number: 7858762
    Abstract: An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: December 28, 2010
    Assignee: Genencor International, Inc.
    Inventors: Katherine D Collier, Edwin Lee, Nicholas Leiva, Thomas B Morrison, Volker Schellenberger, Olga V Selifonova, Adam C Kean
  • Acetolactate Synthase (ALS) Selectable Marker from Trichoderma reesei
    Publication number: 20100273201
    Abstract: A nucleic acid encoding an acetolactate synthase (ALS) protein that provides resistance to ALS inhibitors, e.g., sulphonylurea and imidazolinone compounds, is provided. The nucleic acid may be used as a selectable marker for expression of a protein of interest in host cells.
    Type: Application
    Filed: September 21, 2007
    Publication date: October 28, 2010
    Inventors: Benjamin S. Bower, Nigel Dunn-Coleman, Nicholas Leiva
  • Phosphate limited inducible promoter and a bacillus expression system
    Publication number: 20050079571
    Abstract: An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins.
    Type: Application
    Filed: July 26, 2002
    Publication date: April 14, 2005
    Inventors: Katherine Collier, Edwin Lee, Nicholas Leiva, Thomas Morrison, Volker Schellenberger, Olga Selifonova, Adam Kean