Patents by Inventor Nicholas Marini

Nicholas Marini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cofactors and Methods for Use for Individuals
    Publication number: 20120277180
    Abstract: Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of at least one genetic variant, determining a predisposition to cofactor remediable condition, generating a personalized nutritional advice plan based on the genetic variant. Also provided herein are formulations of cofactors determined by the genetic make-up of the individual and methods of determining and producing these formulations.
    Type: Application
    Filed: September 30, 2010
    Publication date: November 1, 2012
    Applicants: VITAPATH GENETICS, INC, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Nicholas Marini, Jasper Rine, Dennis Austin Gilbert, Bruce Cohen
  • Impaired Alleles of Genes Involved in Metabolic Pathways and Methods for Detecting and Using the Same
    Publication number: 20090281061
    Abstract: The invention is directed to enzyme variants, responsiveness thereof to cofactors, and in vivo assays for testing the activity of enzyme variants as well as the responsiveness thereof to cofactors.
    Type: Application
    Filed: March 27, 2009
    Publication date: November 12, 2009
    Applicant: The Regents of the University of California
    Inventors: Nicholas Marini, Jasper Rine
  • Methods for the identification of inhibitors of an isoprenoid metabolic pathway
    Patent number: 7078169
    Abstract: The present invention relates to methods of identifying genes whose expression is indicative of activation of a particular biochemical or metabolic pathway or a common set of biological reactions or functions in a cell (“regulon indicator genes”) The present invention provides an example of such an indicator gene. The present invention also relates to methods of partially characterizing a gene of unknown function by determining which biological pathways, reactions or functions its expression is associated with, thereby placing the gene within a functional genetic group or “regulon”. These partially characterized genes may be used to identify desirable therapeutic targets of biological pathways of interest (“regulon target genes”) The present invention provides examples of such target genes. Methods for identifying effectors (activators and inhibitors) of regulon target genes are provided. The present invention also provides examples of regulon target gene inhibitors.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: July 18, 2006
    Assignee: Rosetta Inpharmatics LLC
    Inventors: Matthew Ashby, Stewart Scherer, John W. Phillips, Michael Ziman, Nicholas Marini
  • Methods for the identification of reporter and target molecules using comprehensive gene expression profiles
    Publication number: 20030093226
    Abstract: The present invention relates to methods of identifying genes whose expression is indicative of activation of a particular biochemical or metabolic pathway or a common set of biological reactions or functions in a cell (“regulon indicator genes”) The present invention provides an example of such an indicator gene. The present invention also relates to methods of partially characterizing a gene of unknown function by determining which biological pathways, reactions or functions its expression is associated with, thereby placing the gene within a functional genetic group or “regulon”. These partially characterized genes may be used to identify desirable therapeutic targets of biological pathways of interest (“regulon target genes”) The present invention provides examples of such target genes. Methods for identifying effectors (activators and inhibitors) of regulon target genes are provided. The present invention also provides examples of regulon target gene inhibitors.
    Type: Application
    Filed: July 26, 2002
    Publication date: May 15, 2003
    Applicant: Rosetta Inpharmatics, Inc.
    Inventors: Matthew Ashby, Stewart Scherer, John W. Phillips, Michael Ziman, Nicholas Marini
  • Cake removal utensil
    Patent number: 6202309
    Abstract: A utensil comprised of a shaped wire utilizing mechanical separation to facilitate the removal of foodstuffs from their container to eliminate the possibility of breakage.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: March 20, 2001
    Inventors: David Robert Marini, Anthony Nicholas Marini