Patents by Inventor Nicholas Murray Thomson

Nicholas Murray Thomson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8013019
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: September 6, 2011
    Assignee: Pfizer Inc
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Publication number: 20100273758
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: July 1, 2010
    Publication date: October 28, 2010
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Patent number: 7767715
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: August 3, 2010
    Assignee: Pfizer Inc
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Publication number: 20090197912
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: April 8, 2009
    Publication date: August 6, 2009
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Patent number: 7528170
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: May 5, 2009
    Assignee: Pfizer Inc.
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Publication number: 20080267970
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: July 3, 2007
    Publication date: October 30, 2008
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Publication number: 20080193988
    Abstract: The invention relates to a process for the preparation of compounds of formula (I) wherein Q1 is a group selected from formulae (II) & (III) and a group *-NR6-Q2-A or, if appropriate, their pharmaceutically acceptable salts and/or isomers, tautomers, solvates or isotopic variations thereof, as well as intermediates used in said process.
    Type: Application
    Filed: July 10, 2006
    Publication date: August 14, 2008
    Inventors: Iain Robert Gladwell, Pieter David De Koning, Ian Brian Moses, Alan John Pettman, Nicholas Murray Thomson
  • Patent number: 7351742
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: April 1, 2008
    Assignee: Pfizer Inc.
    Inventors: Alan Daniel Brown, Kim James, Charlotte Alice Louise Lane, Ian Brian Moses, Nicholas Murray Thomson
  • Patent number: 7244766
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: July 17, 2007
    Assignee: Pfizer Inc
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Patent number: 7067660
    Abstract: There is provided a process for the production a compound of general formula I: wherein A, R1, R2, R3 and R4 have meanings given in the description, which process comprises the dehydrogenation of a compound of general formula II,
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: June 27, 2006
    Assignee: Pfizer Inc.
    Inventors: Mark Edward Bunnage, Philip Charles Levett, Nicholas Murray Thomson
  • Patent number: 6897306
    Abstract: Compounds of formula (I): and their salts, solvates, prodrugs, etc., wherein the substituents have the values mentioned herein, are Procollagen C-Proteinase (PCP) inhibitors and have utility in conditions mediated by PCP.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: May 24, 2005
    Assignee: Pfizer Products, Inc.
    Inventors: Simon Bailey, Stephane Billotte, Paul Vincent Fish, Kim James, Nicholas Murray Thomson, Andrew Michael Derrick
  • Patent number: 6750363
    Abstract: An efficient and selective process, capable of scale-up, to make itaconate derivatives of formula (IV), and/or succinate derivatives of formula (V) and/or (VI) by asymmetric hydrogenation of the itaconate derivatives. wherein R, R1 and R2 are as defined herein.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: June 15, 2004
    Assignee: Pfizer, Inc.
    Inventors: Andrew Michael Derrick, Nicholas Murray Thomson
  • Publication number: 20040110948
    Abstract: There is provided a process for the production a compound of general formula I: 1
    Type: Application
    Filed: December 1, 2003
    Publication date: June 10, 2004
    Applicant: Pfizer Inc
    Inventors: Mark Edward Bunnage, Philip Charles Levett, Nicholas Murray Thomson
  • Patent number: 6730786
    Abstract: There is provided a process for the production a compound of general formula I: wherein A, R1, R2, R3 and R4 have meanings given in the description, which process comprises the dehydrogenation of a compound of general formula II,
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: May 4, 2004
    Assignee: Pfizer Inc
    Inventors: Mark Edward Bunnage, Philip Charles Levett, Nicholas Murray Thomson
  • Publication number: 20030119807
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: July 16, 2002
    Publication date: June 26, 2003
    Inventors: Simon Bailey, Stephane Billotte, Paul Vincent Fish, Kim James, Nicholas Murray Thomson, Andrew Michael Derrick
  • Patent number: 6511993
    Abstract: Compounds of formula (I) and pharmaceutically-acceptable derivatives thereof, are matrix metalloprotease inhibitors, useful in treatment of conditions mediated by matrix metalloproteases, such as chronic dermal ulcers.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: January 28, 2003
    Inventors: Kevin Neil Dack, Michael Jonathan Fray, Gavin Alistair Whitlock, Mark Llewellyn Lewis, Nicholas Murray Thomson
  • Publication number: 20020188121
    Abstract: An efficient and selective process, capable of scale-up, to make itaconate derivatives of formula (IV), and/or succinate derivatives of formula (V) and/or (VI) by asymmetric hydrogenation of the itaconate derivatives.
    Type: Application
    Filed: July 18, 2002
    Publication date: December 12, 2002
    Inventors: Andrew Michael Derrick, Nicholas Murray Thomson
  • Patent number: 6452041
    Abstract: An efficient and selective process, capable of scale-up, to make itaconate derivatives of formula (IV), and/or succinate derivatives of formula (V) and/or (VI) by asymmetric hydrogenation of the itaconate derivatives. wherein R, R1 and R2 are as defined herein.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: September 17, 2002
    Assignee: Pfizer Inc.
    Inventors: Andrew Michael Derrick, Nicholas Murray Thomson
  • Patent number: 6448278
    Abstract: Compounds of formula (I): and their salts, solvates, prodrugs, etc., wherein the substituents have the values mentioned herein, are Procollagen C-Proteinase (PCP) inhibitors and have utility in conditions mediated by PCP.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: September 10, 2002
    Assignee: Pfizer Inc.
    Inventors: Simon Bailey, Stephane Billotte, Andrew Michael Derrick, Paul Vincent Fish, Kim James, Nicholas Murray Thomson
  • Publication number: 20020058832
    Abstract: An efficient and selective process, capable of scale-up, to make itaconate derivatives of formula (IV), and/or succinate derivatives of formula (V) and/or (VI) by asymmetric hydrogenation of the itaconate derivatives.
    Type: Application
    Filed: October 15, 2001
    Publication date: May 16, 2002
    Inventors: Andrew Michael Derrick, Nicholas Murray Thomson