Patents by Inventor Nicholas Oswald

Nicholas Oswald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8076106
    Abstract: A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: December 13, 2011
    Assignee: Richmond Chemical Corporation
    Inventors: Ian Fotheringham, Nicholas Oswald
  • Publication number: 20090298134
    Abstract: A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.
    Type: Application
    Filed: August 6, 2009
    Publication date: December 3, 2009
    Inventors: Ian Fotheringham, Nicholas Oswald
  • Patent number: 7588923
    Abstract: A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: September 15, 2009
    Assignee: Richmond Chemical Corporation
    Inventors: Ian Fotheringham, Nicholas Oswald
  • Publication number: 20090029401
    Abstract: A method for detecting biofuel producing microbes in a colorimetric assay by providing a microbe, a feedstock, and an assay solution. The assay solution contains an alcohol oxidase, a peroxidase, and a peroxidase co-substrate. The microbe is cultured with the feedstock as part of a culture medium that produces a detectable amount of bioalcohol. The culture medium is contacted with the assay solution to produce a colorimetric reaction to screen for a biofuel producing microbe.
    Type: Application
    Filed: July 24, 2008
    Publication date: January 29, 2009
    Inventors: Ian Fotheringham, Nicole Kaftzik, Nicholas Oswald
  • Publication number: 20080213845
    Abstract: A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.
    Type: Application
    Filed: February 29, 2008
    Publication date: September 4, 2008
    Inventors: Ian Fotheringham, Nicholas Oswald
  • Patent number: 7322926
    Abstract: A centrifugal device comprising: a rotor having a rotor shaft having a longitudinal rotor axis; a holder having an access end, and a holder axis; a location mechanism for locating the holder within the centrifugal device, such that the holder is rotatable about the rotor axis, with the holder axis forming a non-zero angle with the rotor shaft axis, the location mechanism accurately locating the access end of the holder within the centrifugal device, wherein the location mechanism comprises a holding pin having an axis that is substantially perpendicular to the rotor axis, the holding pin being rotatable about the rotor axis.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: January 29, 2008
    Assignee: Sophion Bioscience A/S
    Inventors: Jorgen Due, Karen-Margrethe Krzywkowski, Nicholas Oswald, John Larsen, Henrik Vennerberg
  • Patent number: 7288785
    Abstract: The present invention relates to a substantially planar substrate for use in patch clamp analysis of the electrophysiological properties of a cell membrane comprising a glycocalyx, wherein the substrate comprises an aperture having a rim, the rim being adapted to form a gigaseal upon contact with the cell membrane, The invention further provides a method of making such a substrate and method for analysing the electrophysiological properties of a cell membrane comprising a glycocalyx.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: October 30, 2007
    Assignee: Sophion Bioscience A/S
    Inventors: Ras Kaas Vestergaard, Niels Willumsen, Nicholas Oswald, Jonatan Kutchinsky, Dirk Reuter, Rafael Taboryski
  • Publication number: 20060287182
    Abstract: A centrifugal device comprising: a rotor having a rotor shaft having a longitudinal rotor axis; a holder having an access end, and a holder axis; location means for locating the holder within the centrifugal device, such that the holder is rotatable about the rotor axis, with the holder axis forming a non-zero angle with the rotor shaft axis, the location means accurately locating the access end of the holder within the centrifugal device, wherein the location means comprises a holding pin having an axis that is substantially perpendicular to the rotor axis, the holding pin being rotatable about the rotor axis.
    Type: Application
    Filed: February 23, 2004
    Publication date: December 21, 2006
    Applicant: SOPHION BIOSCIENCE A/S
    Inventors: Jorgen Due, Karen-Margarethe Krzywkowksi, Nicholas Oswald, John Larsen, Henrik Vennerberg
  • Publication number: 20050212095
    Abstract: The present invention relates to a substantially planar substrate for use in patch clamp analysis of the electrophysiological properties of a cell membrane comprising a glycocalyx, wherein the substrate comprises an aperture having a rim, the rim being adapted to form a gigaseal upon contact with the cell membrane. The invention further provides a method of making such a substrate and method for analysing the electrophysiological properties of a cell membrane comprising a glycocalyx.
    Type: Application
    Filed: April 17, 2003
    Publication date: September 29, 2005
    Applicant: Sophion Bioscience A/S
    Inventors: Ras Vestergaard, Niels Willumsen, Nicholas Oswald, Jonatan Kutchinsky, Dirk Reuter, Rafael Taboryski
  • Publication number: 20040005696
    Abstract: The present invention retates to a substantially planar substrate for use in patch clamp analysis of the electrophysiological properties of a cell membrane comprising a glycocalyx, wherein the substrate comprises an aperture having a rim, the rim being adapted to form a gigaseal upon contact with the cell membrane, The invention further provides a method of making such a substrate and method for analysing the electrophysiological properties of a cell membrane comprising a glycocalyx.
    Type: Application
    Filed: April 17, 2003
    Publication date: January 8, 2004
    Inventors: Ras Kaas Vestergaard, Niels Willumsen, Nicholas Oswald, Jonatan Kutchinsky, Dirk Reuter, Rafael Taboryski