Patents by Inventor Nicholas Palermo

Nicholas Palermo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14-3-3 TARGETING PEPTIDES FOR CANCER TREATMENT
    Publication number: 20230312645
    Abstract: Systems and methods for treatment of squamous cell carcinoma or other cancer utilizing targeting peptides are described. The targeting peptides interact with SCC cells or other cancerous cells to block or interfere with 14-3-3? heterodimerization or CDC25A binding to 14-3-3?. A peptide composition embodiment includes, but is not limited to, at least one of a first targeting peptide comprising a structure of Trp-Tyr-Trp-Lys-NH2 (SEQ ID NO: 1), a second targeting peptide comprising a structure of phospho-Ser178; Ac-Thr-Gln-Arg-Gln-Asn-Ser-(PO32?)-Ala-Pro-Arg-Met-Leu-Ser-Ser-Asn-NH2 (SEQ ID NO: 2), and a third targeting peptide comprising a structure of phospho-Thr507 residue; Ac-Arg-Thr-Lys-Ser-Arg-Thr(PO32?)-Trp-Ala-Gly-Glu-Lys-Ser-Lys-Arg-NH2 (SEQ ID NO: 3).
    Type: Application
    Filed: December 6, 2022
    Publication date: October 5, 2023
    Inventors: Laura Hansen, Sandor Lovas, Nicholas Palermo
  • 14-3-3 targeting peptides for cancer treatment
    Patent number: 11685766
    Abstract: Systems and methods for treatment of squamous cell carcinoma or other cancer utilizing targeting peptides are described. The targeting peptides interact with SCC cells or other cancerous cells to block or interfere with 14-3-3? heterodimerization or CDC25A binding to 14-3-3?. A peptide composition embodiment includes, but is not limited to, at least one of a first targeting peptide comprising a structure of Ac-Gln-Arg-Gln-Asn-Ser-(PO32?)-Ala-Pro-Ala-Arg-NH2 (SEQ ID NO: 4) and a second targeting peptide comprising a structure of Ac-Arg-Thr-Lys-Ser-Arg-Thr(PO32?)-Trp-Ala-Gly-NH2 (SEQ ID NO: 5), and a third targeting peptide comprising a modification of or a substituted derivative of the peptide of SEQ ID NO: 4 or SEQ ID NO: 5.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: June 27, 2023
    Assignees: Creighton University, Nutech Ventures
    Inventors: Laura Hansen, Sandor Lovas, Nicholas Palermo
  • 14-3-3 targeting peptides for cancer treatment
    Patent number: 11518784
    Abstract: Systems and methods for treatment of squamous cell carcinoma or other cancer utilizing targeting peptides are described. The targeting peptides interact with SCC cells or other cancerous cells to block or interfere with 14-3-3? heterodimerization or CDC25A binding to 14-3-3?. A peptide composition embodiment includes, but is not limited to, at least one of a first targeting peptide comprising a structure of Trp-Tyr-Trp-Lys-NH2 (SEQ ID NO: 1), a second targeting peptide comprising a structure of phospho-Ser178; Ac-Thr-Gln-Arg-Gln-Asn-Ser-(PO32?)-Ala-Pro-Arg-Met-Leu-Ser-Ser-Asn-NH2 (SEQ ID NO: 2), and a third targeting peptide comprising a structure of phospho-Thr507 residue; Ac-Arg-Thr-Lys-Ser-Arg-Thr(PO32?)-Trp-Ala-Gly-Glu-Lys-Ser-Lys-Arg-NH2 (SEQ ID NO: 3).
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: December 6, 2022
    Assignees: CREIGHTON UNIVERSITY, NUTECH VENTURES
    Inventors: Laura Hansen, Sandor Lovas, Nicholas Palermo
  • Methods of treating or preventing Zika virus infection
    Patent number: 11135219
    Abstract: This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: October 5, 2021
    Assignee: NUtech Ventures
    Inventors: Shi-hua Xiang, Nicholas Palermo, Asit K. Pattnaik, Aryamav ' Pattnaik
  • 14-3-3 TARGETING PEPTIDES FOR CANCER TREATMENT
    Publication number: 20210277060
    Abstract: Systems and methods for treatment of squamous cell carcinoma or other cancer utilizing targeting peptides are described. The targeting peptides interact with SCC cells or other cancerous cells to block or interfere with 14-3-3? heterodimerization or CDC25A binding to 14-3-3?. A peptide composition embodiment includes, but is not limited to, at least one of a first targeting peptide comprising a structure of Ac-Gln-Arg-Gln-Asn-Ser-(PO32?)-Ala-Pro-Ala-Arg-NH2 (SEQ ID NO: 4) and a second targeting peptide comprising a structure of Ac-Arg-Thr-Lys-Ser-Arg-Thr(PO32?)-Trp-Ala-Gly-NH2 (SEQ ID NO: 5), and a third targeting peptide comprising a modification of or a substituted derivative of the peptide of SEQ ID NO: 4 or SEQ ID NO: 5.
    Type: Application
    Filed: May 7, 2021
    Publication date: September 9, 2021
    Inventors: Laura Hansen, Sandor Lovas, Nicholas Palermo
  • 14-3-3 TARGETING PEPTIDES FOR CANCER TREATMENT
    Publication number: 20210107940
    Abstract: Systems and methods for treatment of squamous cell carcinoma or other cancer utilizing targeting peptides are described. The targeting peptides interact with SCC cells or other cancerous cells to block or interfere with 14-3-3? heterodimerization or CDC25A binding to 14-3-3?. A peptide composition embodiment includes, but is not limited to, at least one of a first targeting peptide comprising a structure of Trp-Tyr-Trp-Lys-NH2 (SEQ ID NO: 1), a second targeting peptide comprising a structure of phospho-Ser178; Ac-Thr-Gln-Arg-Gln-Asn-Ser-(PO32?)-Ala-Pro-Arg-Met-Leu-Ser-Ser-Asn-NH2 (SEQ ID NO: 2), and a third targeting peptide comprising a structure of phospho-Thr507 residue; Ac-Arg-Thr-Lys-Ser-Arg-Thr(PO32?)-Trp-Ala-Gly-Glu-Lys-Ser-Lys-Arg-NH2 (SEQ ID NO: 3).
    Type: Application
    Filed: May 8, 2020
    Publication date: April 15, 2021
    Inventors: Laura Hansen, Sandor Lovas, Nicholas Palermo
  • SYSTEM, DEVICE AND METHOD FOR RECONDITIONING A SUBSTRATE SUPPORT
    Publication number: 20210053177
    Abstract: A treatment tool for reconditioning the top surfaces of a plurality of projections of a substrate support in a lithographic tool. The treatment tool includes a reconditioning surface which is rough relative to smoothed top surfaces of the projections and which reconditioning surface has material harder than that of the material of the top surfaces of the projections. A reconditioning method involves causing an interaction between the reconditioning surface of the treatment tool and the top surfaces of the projections of the substrate support, so as to leave these top surfaces rougher than they were prior to the interaction.
    Type: Application
    Filed: January 24, 2019
    Publication date: February 25, 2021
    Applicants: ASML NETHERLANDS B.V., ASML HOLDING N.V.
    Inventors: Bert Dirk SCHOLTEN, Satish ACHANTA, Aydar AKCHURIN, Pavlo ANTONOV, Coen Hubertus Matheus BALTIS, Jeroen BOUWKNEGT, Ann-Sophie m. FARLE, Christopher John MASON, Ralph Nicholas PALERMO, Thomas POIESZ, Yuri Johannes Gabriel VAN DE VIJVER, Jimmy Matheus Wilhelmus VAN DE WINKEL
  • METHODS OF TREATING OR PREVENTING ZIKA VIRUS INFECTION
    Publication number: 20200316059
    Abstract: This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 8, 2020
    Inventors: Shi-hua Xiang, Nicholas Palermo, Asit K. Pattnaik, Aryamav ` Pattnaik
  • METHODS OF TREATING OR PREVENTING ZIKA VIRUS INFECTION
    Publication number: 20190167670
    Abstract: This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection.
    Type: Application
    Filed: October 31, 2018
    Publication date: June 6, 2019
    Inventors: Shi-hua Xiang, Nicholas Palermo, Asit K. Pattnaik, Aryamav Pattnaik