Patents by Inventor Nicholas R. Cozzarelli

Nicholas R. Cozzarelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid magnet devices for molecule manipulation and small scale high gradient-field applications
    Patent number: 7474184
    Abstract: The present disclosure provides a high performance hybrid magnetic structure made from a combination of permanent magnets and ferromagnetic pole materials which are assembled in a predetermined array. The hybrid magnetic structure provides means for separation and other biotechnology applications involving holding, manipulation, or separation of magnetizable molecular structures and targets. Also disclosed are hybrid magnetic tweezers able to exert approximately 1 nN of force to 4.5 ?m magnetic bead. The maximum force was experimentally measured to be ˜900 pN which is in good agreement with theoretical estimations and other measurements. In addition, a new analysis scheme that permits fast real-time position measurement in typical geometry of magnetic tweezers has been developed and described in detail.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: January 6, 2009
    Assignee: The Regents of the University of California
    Inventors: David E. Humphries, Seok-Cheol Hong, Linda A. Cozzarelli, legal representative, Martin J. Pollard, Nicholas R. Cozzarelli