Patents by Inventor Nicholas R. Husni

Nicholas R. Husni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic screens for type 1 diabetes (IDDM)
    Patent number: 6620583
    Abstract: The present invention features a method for identifying genes or proteins important in insulin-dependent diabetes mellitus (IDDM). The genes or proteins are useful in identifying IDDM-susceptible individuals, and in identifying and testing potential therapeutic agents for the treatment of IDDM.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: September 16, 2003
    Assignee: Boston Medical Center Corporation
    Inventors: Barbara E. Corkey, Nicholas R. Husni
  • Novel diagnostic screens for type 1 diabetes (IDDM)
    Publication number: 20020177123
    Abstract: The present invention features methods for diagnosing insulin-dependent diabetes mellitus (IDDM) in a test subject, for example a subject at risk of developing IDDM, which involve detecting hyper-responsive Ca2+ mobilization in cells obtained from the test subject. Hyper-responsive Ca2+ mobilization can be detected in cells contacted with a stimulatory agent, preferably in cells contacted with a potentiating agent and a stimulatory agent. Methods of the present invention include comparing Ca2+ mobilization in cells from the test subject to Ca2+ mobilization in cells from a control subject. The present invention further features kits for use in the detection of IDDM.
    Type: Application
    Filed: July 7, 2002
    Publication date: November 28, 2002
    Applicant: Trustees of Boston University
    Inventors: Barbara E. Corkey, Nicholas R. Husni
  • Novel diagnostic screens type 1 diabetes (IDDM)
    Publication number: 20020018987
    Abstract: The present invention features methods for diagnosing insulin-dependent diabetes mellitus (IDDM) in a test subject, for example a subject at risk of developing IDDM, which involve detecting hyper-responsive Ca2+ mobilization in cells obtained from the test subject. Hyper-responsive Ca2+ mobilization can be detected in cells contacted with a stimulatory agent, preferably in cells contacted with a potentiating agent and a stimulatory agent. Methods of the present invention include comparing Ca2+ mobilization in cells from the test subject to Ca2+ mobilization in cells from a control subject. The present invention further features kits for use in the detection of IDDM.
    Type: Application
    Filed: October 5, 2001
    Publication date: February 14, 2002
    Applicant: Trustees of Boston University
    Inventors: Barbara E. Corkey, Nicholas R. Husni
  • Diagnostic screens for type 1 diabetes (IDDM)
    Patent number: 6300055
    Abstract: The present invention features methods for diagnosing insulin-dependent diabetes mellitus (IDDM) in a test subject, for example a subject at risk of developing IDDM, which involve detecting hyper-responsive Ca2+ mobilization in cells obtained from the test subject. Hyper-responsive Ca2+ mobilization can be detected in cells contacted with a stimulatory agent, preferably in cells contacted with a potentiating agent and a stimulatory agent. Methods of the present invention include comparing Ca2+ mobilization in cells from the test subject to Ca2+ mobilization in cells from a control subject. The present invention further features kits for use in the detection of IDDM.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: October 9, 2001
    Assignee: Trustees of Boston University
    Inventors: Barbara E. Corkey, Nicholas R. Husni