Patents by Inventor Nicholas R. Waterfield

Nicholas R. Waterfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LEADER SEQUENCE
    Publication number: 20230076614
    Abstract: The present invention provides use of a Photorhabdus Virulence Cassettes (PVC) effector leader sequence, for packaging a payload into a PVC Needle Complex, and related methods for manufacturing a packaged PVC Needle Complex. The payload is one or more selected from a polypeptide, a nucleic acid, or a combination thereof, and the leader sequence and the payload form an effector fusion that is distinct from a wild-type PVC effector protein.
    Type: Application
    Filed: June 5, 2020
    Publication date: March 9, 2023
    Applicant: THE UNIVERSITY OF WARWICK
    Inventors: Nicholas R. WATERFIELD, Joseph HEALEY, Alexia HAPESHI
  • DNA sequences from tcd genomic region of
    Patent number: 7777100
    Abstract: Nucleotide sequences for seven genes, tccC4, tcdA3, tcdA2, tcdB2, tccC3, tcdA4, tccC5, from the tcd genomic region of Photorhabdus luminescens W-14, are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: August 17, 2010
    Inventors: Richard H. ffrench-Constant, Nicholas R. Waterfield
  • DNA sequences from tcd genomic region of photorhabdus luminescens
    Publication number: 20080168588
    Abstract: Nucleotide sequences for seven genes, tccC4, tcdA3, tcdA2, tcdB2, tccC3, tcdA4, tccC5, from the tcd genomic region of Photorhabdus luminescens W-14, are useful in heterologous expression of orally active insect toxins.
    Type: Application
    Filed: July 31, 2007
    Publication date: July 10, 2008
    Inventors: Richard H. ffrench-Constant, Nicholas R. Waterfield
  • tcdB2 protein from W-14
    Patent number: 7268275
    Abstract: TcdB2, a protein from Photorhabdus luminescens W-14, and nucleotide sequences encoding TcdB2, are useful for enhancing expression of orally active Photorhabdus luminescens insecticidal toxins in heterologous organisms.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: September 11, 2007
    Assignee: University of Bath
    Inventors: Richard H. ffrench-Constant, Nicholas R. Waterfield
  • DNA Sequences from
    Patent number: 7161062
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: January 9, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Richard H. Ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
  • DNA sequences from Tcd genomic region of photorhabdus luminescens
    Publication number: 20040103455
    Abstract: Nucleotide sequences for seven genes, tccC4, tcdA3, tcdA2, tcdB2, tccC3, tcdA4, tccC5, from the tcd genomic region of Photorhabdus luminescens W-14, are useful in heterologous expression of orally active insect toxins.
    Type: Application
    Filed: November 12, 2003
    Publication date: May 27, 2004
    Inventors: Richard H. Ffrench-Constant, Nicholas R. Waterfield
  • DNA sequences from photorhabdus luminescens
    Patent number: 6639129
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: October 28, 2003
    Assignees: Wisconsin Alumni Research Foundation, University of Bath
    Inventors: Richard H. ffrench-Constant, David J. Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield
  • DNA sequences from photorhabdus luminescens
    Publication number: 20020078478
    Abstract: Nucleotide sequences for two genes, tcdB and tccC2, from the tcd genomic region of Photorhabdus luminescens W-14 are useful in heterologous expression of orally active insect toxins.
    Type: Application
    Filed: March 26, 2001
    Publication date: June 20, 2002
    Inventors: Richard H. Ffrench-Constant, David Bowen, Thomas A. Rocheleau, Nicholas R. Waterfield