Patents by Inventor Nicholas Restifo

Nicholas Restifo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Making, Compositions Comprising, and Methods of Using Rejuvenated T Cells
    Publication number: 20250154458
    Abstract: The present disclosure relates generally to methods of producing rejuvenated T cells, comprising, contacting T cells with at least one reprogramming factor and reactivating the contacted cells; and compositions and methods of using same. The present disclosure also describes cell populations prepared according to methods described herein. The disclosure also provides for methods of treating patients using cell populations prepared by the methods described herein.
    Type: Application
    Filed: August 16, 2024
    Publication date: May 15, 2025
    Applicant: Lyell Immunopharma, Inc.
    Inventors: Raul E. VIZCARDO SAKODA, Nicholas RESTIFO, I, Richard D. KLAUSNER, Yin HUANG, Takuya MAEDA, Naritaka TAMAOKI, Yasuhiro YAMAZAKI
  • Methods for making, compositions comprising, and methods of using rejuvenated T cells
    Patent number: 12091682
    Abstract: The present disclosure relates generally to methods of producing rejuvenated T cells, comprising, contacting T cells with at least one reprogramming factor and reactivating the contacted cells; and compositions and methods of using same. The present disclosure also describes cell populations prepared according to methods described herein. The disclosure also provides for methods of treating patients using cell populations prepared by the methods described herein.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: September 17, 2024
    Assignee: Lyell Immunopharma, Inc.
    Inventors: Raul E. Vizcardo Sakoda, Nicholas Restifo, Richard D. Klausner, Yin Huang, Takuya Maeda, Naritaka Tamaoki, Yasuhiro Yamazaki
  • METHODS FOR MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING REJUVENATED T CELLS
    Publication number: 20220162551
    Abstract: The present disclosure relates generally to methods of producing rejuvenated T cells, comprising, contacting T cells with at least one reprogramming factor and reactivating the contacted cells; and compositions and methods of using same. The present disclosure also describes cell populations prepared according to methods described herein. The disclosure also provides for methods of treating patients using cell populations prepared by the methods described herein.
    Type: Application
    Filed: November 23, 2021
    Publication date: May 26, 2022
    Inventors: Raul E. Vizcardo Sakoda, Nicholas Restifo, Richard D. Klausner, Yin Huang, Takuya Maeda, Naritaka Tamaoki, Yasuhiro Yamazaki
  • Heterologous boosting immunizations
    Publication number: 20050100558
    Abstract: This invention describes methods of vaccination for the effective generation of an antigen-specific immune response. More particularly, this invention describes the use of heterologous vaccination vectors for eliciting an enhanced boosting immunization response. Methods of treatment and prevention of diseases using the vaccination schemes of the invention are also provided.
    Type: Application
    Filed: December 8, 2004
    Publication date: May 12, 2005
    Applicant: The Government of the United States of America, as Represented by the Secretary, Department of Healt
    Inventors: Ronald Chamberlain, Kari Irvine, Steven Rosenberg, Nicholas Restifo