Patents by Inventor Nicholas Scorah

Nicholas Scorah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kinase inhibitors
    Patent number: 8288536
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: October 16, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • KINASE INHIBITORS
    Publication number: 20120252761
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: April 2, 2012
    Publication date: October 4, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Jason W. Brown, Qing Dong, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Hasanthi Wijesekera
  • Kinase inhibitors
    Patent number: 8278450
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: October 2, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jason W. Brown, Qing Dong, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Hasanthi Wijesekera
  • Hexahydrooxazinopterine compounds
    Patent number: 8268819
    Abstract: The present invention relates to intermediates of the formula wherein G1 is N; G2 is selected from the group consisting of C?O and CH2; X is a halogen; and the other groups are defined herein.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: September 18, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Bohan Jin, Nicholas Scorah, Qing Dong
  • N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES
    Publication number: 20120220575
    Abstract: Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein Ar, R1, R2, R3, G1, G2, and m are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating inflammatory disorders, cardiovascular disease, cancer, and other conditions associated with PI3K?.
    Type: Application
    Filed: February 24, 2012
    Publication date: August 30, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Edcon Chang, Tony Gibson, Bohan Jin, Nicholas Scorah, Qing Dong
  • HEXAHYDROOXAZINOPTERINE COMPOUNDS
    Publication number: 20120178924
    Abstract: The present invention relates to intermediates of the formula wherein G1 is N; G2 is selected from the group consisting of C?O and CH2; X is a halogen; and the other groups are defined herein.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 12, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Bohan Jin, Nicholas Scorah, Qing Dong
  • Hexahydrooxazinopterine compounds
    Patent number: 8163755
    Abstract: The present invention provides mTOR inhibitors of the formula wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods of making the compounds and intermediates thereof; and methods of using the compounds.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: April 24, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Bohan Jin, Nicholas Scorah, Qing Dong
  • KINASE INHIBITORS
    Publication number: 20120095233
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: April 16, 2008
    Publication date: April 19, 2012
    Applicant: TAKEDA SAN DIEGO, INC.
    Inventors: Jason W. Brown, Qing Dong, Bheema R. Paraselli, Jeffrey A. Stafford, Michael B. Wallace, Hasanthi Wijesekera, Nicholas Scorah
  • Kinase inhibitors
    Patent number: 8119655
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: February 21, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace
  • HEXAHYDROOXAZINOPTERINE COMPOUNDS
    Publication number: 20110053921
    Abstract: The present invention provides mTOR inhibitors of the formula wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods of making the compounds and intermediates thereof; and methods of using the compounds.
    Type: Application
    Filed: August 26, 2010
    Publication date: March 3, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Bohan Jin, Nicholas Scorah, Qing Dong
  • KINASE INHIBITORS
    Publication number: 20100216765
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: April 6, 2010
    Publication date: August 26, 2010
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • KINASE INHIBITORS
    Publication number: 20100190816
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: February 18, 2010
    Publication date: July 29, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Qing Dong, Bheema R. Paraselli, Nicholas Scorah, Michael B. Wallace, Jeffrey A. Stafford
  • KINASE INHIBITORS
    Publication number: 20100160633
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: February 17, 2010
    Publication date: June 24, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Jason W. Brown, Qing Dong, Bheema R. Paraselli, Jeffrey A. Stafford, Xianchang Gong, Yan Liu, Nicholas Scorah, Michael B. Wallace
  • MAPK/ERK KINASE INHIBITORS
    Publication number: 20100130518
    Abstract: Compounds of the following formula are provided for use with MEK (I): wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: December 18, 2007
    Publication date: May 27, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Qing Dong, Xianchang Gong, Stephen W. Kaldor, Toufike Kanouni, Nicholas Scorah, Michael B. Wallace, Feng Zhou
  • Kinase inhibitors
    Patent number: 7713973
    Abstract: Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: May 11, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Qing Dong, David J. Hosfield, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Michael B. Wallace, Zhiyuan Zhang
  • KINASE INHIBITORS
    Publication number: 20090312288
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: April 16, 2009
    Publication date: December 17, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Jason W. Brown, Qing Dong, Anthony R. Gangloff, Bheema R. Paraselli, Nicholas Scorah, Jeffrey A. Stafford, Sanjib Das, Jonathon S. Salsbury
  • KINASE INHIBITORS
    Publication number: 20090156557
    Abstract: Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: April 15, 2008
    Publication date: June 18, 2009
    Applicant: TAKEDA SAN DIEGO, INC.
    Inventors: Jason W. Brown, Qing Dong, Bheema R. Paraselli, Jeffrey A. Stafford, Xianchang Gong, Yan Liu, Nicholas Scorah, Michael B. Wallace
  • MAPK/ERK KINASE INHIBITORS
    Publication number: 20090124595
    Abstract: Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: November 7, 2008
    Publication date: May 14, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: MarK Adams, Qing Dong, Toufike Kanouni, Stephen W. Kaldor, Nicholas Scorah, Michael B. Wallace
  • MAPK/ERK KINASE INHIBITORS
    Publication number: 20080255160
    Abstract: Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: December 18, 2007
    Publication date: October 16, 2008
    Inventors: Qing Dong, Xianchang Gong, Stephen W. Kaldor, Toufike Kanouni, Nicholas Scorah, Michael B. Wallace, Feng Zhou
  • KINASE INHIBITORS
    Publication number: 20070117816
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: October 9, 2006
    Publication date: May 24, 2007
    Inventors: Jason Brown, Sanjib Das, Qing Dong, Xianchang Gong, Stephen Kaldor, Yan Liu, Bheema Paraselli, Nicholas Scorah, Jeffrey Stafford, Michael Wallace