Patents by Inventor Nicholas Simon Faithfull

Nicholas Simon Faithfull has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030056788
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Application
    Filed: August 14, 2001
    Publication date: March 27, 2003
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Publication number: 20020082485
    Abstract: Systems and methods are described for calculating, in real-time, various oxygenation parameters including total oxygen transport, mixed venous blood oxygen tension and mixed venous blood oxyhemoglobin saturation in a patient. The system preferably uses a computer, an arterial pressure line and a blood chemistry monitor to assist a physician in accurately determining when to give a patient a blood transfusion or otherwise alter the clinical management of that patient.
    Type: Application
    Filed: November 6, 2001
    Publication date: June 27, 2002
    Inventors: Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: 6390977
    Abstract: Systems are methods described for calculating, in real-time, various oxygenation parameters including total oxygen transport, mixed venous blood oxygen tension and mixed venous blood oxyhemoglobin saturation in a patient. The system preferably uses a computer, an arterial pressure line and a blood chemistry monitor to assist a physician in accurately determining when to give a patient a blood transfusion or otherwise alter the clinical management of that patient.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: May 21, 2002
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: 6289892
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Grant
    Filed: March 9, 2000
    Date of Patent: September 18, 2001
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Patent number: 6234963
    Abstract: A system and method is described for determining and graphically displaying oxygenation states of a patient in real time. The system is non-invasive and can display information to a physician that is intuitive. Various display objects are described for illustrating the output of oxygenation values. The display objects reflect the in vivo physiology that they measure, thus making interpretation of the measured values very intuitive.
    Type: Grant
    Filed: February 9, 1998
    Date of Patent: May 22, 2001
    Assignees: Alliance Pharmaceutical Corp., The Trustees of Dartmouth College
    Inventors: George T. Blike, Nicholas Simon Faithfull, Glenn Rhoades
  • Patent number: 6119687
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: September 19, 2000
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Patent number: 6041777
    Abstract: Methods and apparatus are provided which allow for closed-circuit ventilation for the treatment or diagnosis of disorders. The closed-circuit ventilation apparatus of the present invention provide a closed-circuit respirator that isolates the gas flow path from the ventilator apparatus. This allows the prolonged administration of expensive materials such as fluorochemicals without excessive loss due to evaporation. As such the provided methods an apparatus are particularly applicable to liquid ventilation including partial liquid ventilation and total liquid ventilation.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: March 28, 2000
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Ernest G. Schutt
  • Patent number: 6007774
    Abstract: A method for treating conditions associated with ischemia or infarct is disclosed which includes the steps of administering a biocompatible non-blood oxygen carrier while monitoring one or more oxygenation indices to maintain oxygenation of the patient's tissues at or above a predetermined level.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: December 28, 1999
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Peter E. Keipert, Duane J. Roth, Ronald M. Hopkins
  • Patent number: 5865784
    Abstract: A method for hemodiluting a patient is disclosed which includes the steps of administering a biocompatible oxygen carrier in conjunction with surgery or organ ischemia or infarct while assessing the patient's PvO.sub.2 or other oxygenation indices, and administering to the patient additional oxygen carrier or autologous blood in response to the PvO.sub.2 value if necessary to maintain the PvO.sub.2 at or above the desired level.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 2, 1999
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Peter E. Keipert, Duane J. Roth, Ronald M. Hopkins
  • Patent number: 5853003
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Grant
    Filed: August 7, 1997
    Date of Patent: December 29, 1998
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Patent number: 5655521
    Abstract: The present invention includes a method for treating a patient in need of facilitated oxygen delivery through the lungs, additional lung surfactant, removal of material from inside the lung, or inflation of collapsed portions of the lung, comprising the step of introducing into the lung of the patient an effective therapeutic amount of a fluorocarbon liquid, the amount not exceeding the functional residual capacity of the lung of the patient upon exhalation taking into account any positive and expiratory pressure applied to the patient's lung. The method may also comprise the additional step of providing an oxygen-containing breathing gas to the patient while the fluorocarbon liquid is in the lung.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: August 12, 1997
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Nicholas Simon Faithfull, Jeffry Greg Weers
  • Patent number: RE38081
    Abstract: A method for hemodiluting a patient is disclosed which includes the steps of administering a biocompatible oxygen carrier in conjunction with surgery or organ ischemia or infarct while assessing the patient's PvO2 or other oxygenation indices, and administering to the patient additional oxygen carrier or autologous blood in response to the PvO2 value if necessary to maintain the PvO2 at or above the desired level.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: April 15, 2003
    Inventors: Nicholas Simon Faithfull, Peter E. Keipert, Duane J. Roth, Ronald M. Hopkins