Patents by Inventor Nicholas Sofroniew

Nicholas Sofroniew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Large field of view, high resolution microscope
    Patent number: 10901194
    Abstract: A microscope system including: a source of light; a sample objective configured for focusing the light at a focal plane within a sample; a remote focus unit configured for changing a position of the focal plane along an axis perpendicular to the focal plane; one or more optical element configured for directing the focused light to a location within the focal plane; and a detector configured for detecting light emitted from the focal plane within the sample; wherein the one or more optical element is located after the remote focus unit along a beam path of the light from the source to the sample objective, such that the changing the position of the focal plane along the axis is performed before the directing the focused light to the location within the focal plane.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: January 26, 2021
    Assignee: Howard Hughes Medical Institute
    Inventors: Karel Svoboda, Daniel Flickinger, Nicholas Sofroniew
  • Large field of view, high resolution microscope
    Patent number: 10295811
    Abstract: A microscope system including: a source of light; a sample objective configured for focusing the light at a focal plane within a sample; a remote focus unit configured for changing a position of the focal plane along an axis perpendicular to the focal plane; one or more optical element configured for directing the focused light to a location within the focal plane; and a detector configured for detecting light emitted from the focal plane within the sample; wherein the one or more optical element is located after the remote focus unit along a beam path of the light from the source to the sample objective, such that the changing the position of the focal plane along the axis is performed before the directing the focused light to the location within the focal plane.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: May 21, 2019
    Assignee: Howard Hughes Medical Institute
    Inventors: Karel Svoboda, Daniel Flickinger, Nicholas Sofroniew
  • LARGE FIELD OF VIEW, HIGH RESOLUTION MICROSCOPE
    Publication number: 20190101735
    Abstract: A microscope system including: a source of light; a sample objective configured for focusing the light at a focal plane within a sample; a remote focus unit configured for changing a position of the focal plane along an axis perpendicular to the focal plane; one or more optical element configured for directing the focused light to a location within the focal plane; and a detector configured for detecting light emitted from the focal plane within the sample; wherein the one or more optical element is located after the remote focus unit along a beam path of the light from the source to the sample objective, such that the changing the position of the focal plane along the axis is performed before the directing the focused light to the location within the focal plane.
    Type: Application
    Filed: November 15, 2018
    Publication date: April 4, 2019
    Inventors: Karel Svoboda, Daniel Flickinger, Nicholas Sofroniew
  • LARGE FIELD OF VIEW, HIGH RESOLUTION MICROSCOPE
    Publication number: 20170123196
    Abstract: A microscope system including: a source of light; a sample objective configured for focusing the light at a focal plane within a sample; a remote focus unit configured for changing a position of the focal plane along an axis perpendicular to the focal plane; one or more optical element configured for directing the focused light to a location within the focal plane; and a detector configured for detecting light emitted from the focal plane within the sample; wherein the one or more optical element is located after the remote focus unit along a beam path of the light from the source to the sample objective, such that the changing the position of the focal plane along the axis is performed before the directing the focused light to the location within the focal plane.
    Type: Application
    Filed: November 1, 2016
    Publication date: May 4, 2017
    Inventors: Karel Svoboda, Daniel Flickinger, Nicholas Sofroniew