Patents by Inventor Nicholas Topley

Nicholas Topley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying a bacterial infection
    Patent number: 10564161
    Abstract: The present application concerns a method for identifying the nature of a bacterial infection from a peritoneal sample, in particular, whether it is a Gram-negative or Gram-positive infection, based upon the determination of one or more cellular and/or humoral markers in a sample.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: February 18, 2020
    Assignee: UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED
    Inventors: Matthias Eberl, Nicholas Topley, Chan-yu Lin
  • Method for identifying a bacterial infection
    Patent number: 10209255
    Abstract: Method for identifying a bacterial infection The present application concerns a method for identifying the nature of a bacterial infection from a peritoneal sample, in particular, whether it is a Gram-negative or Gram-positive infection, based upon the determination of one or more cellular and/or humoral markers in a sample.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: February 19, 2019
    Assignee: UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED
    Inventors: Matthias Eberl, Nicholas Topley, Chan-Yu Lin
  • IL-6/IL-6R Fusion Protein
    Publication number: 20090252705
    Abstract: The present invention relates to a fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule. The present invention also relates to a nucleic acid encoding the fusion protein, methods of producing the fusion protein, and the use of the fusion protein in the treatment of infectious diseases and in inflammatory and immunological disorders.
    Type: Application
    Filed: June 10, 2009
    Publication date: October 8, 2009
    Applicant: University College Cardiff Consultants Limited
    Inventors: Simon Arnett Jones, Nicholas Topley
  • IL-6/IL-6R fusion protein
    Publication number: 20070172458
    Abstract: The present invention relates to a fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule. The present invention also relates to a nucleic acid encoding the fusion protein, methods for producing the fusion protein and the use of the fusion protein in the treatment of infectious diseases and inflammatory and immunological disorders.
    Type: Application
    Filed: March 29, 2007
    Publication date: July 26, 2007
    Applicants: University College Cardiff Consultants Limited, University of Wales College of Medicine
    Inventors: Simon Jones, Nicholas Topley
  • Fusion protein
    Publication number: 20050064558
    Abstract: The present invention relates to a fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule. The present invention also relates to a nucleic acid encoding the fusion protein, methods for producing the fusion protein and the use of the fusion protein in the treatment of infectious diseases and inflammatory and immunological disorders.
    Type: Application
    Filed: August 2, 2002
    Publication date: March 24, 2005
    Inventors: Simon Jones, Nicholas Topley