Abstract: The present disclosure relates generally to systems and processes for assessing and differentiating asthma and chronic obstructive pulmonary disease (COPD) in a patient, and more specifically to computer-based systems and processes for providing a predicted diagnosis of asthma and/or COPD. In accordance with one or more examples, a computing system receives a set of patient data corresponding to a first patient and determines whether the set of patient data satisfies a set of one or more data-correlation criteria. If the set of one or more data-correlation criteria are satisfied, the computing system applies a first diagnostic model to the set of patient data and determines a first predicted diagnosis of asthma and/or COPD. If the set of one or more data-correlation criteria are not satisfied, the computing system applies a second diagnostic model to the set of patient data and determines a second predicted diagnosis of asthma and/or COPD.

Abstract: There are provided systems, devices and methods for operating a housing for an electronic device as an input/output (I/O) device. In one embodiment, an electronic device includes a housing configured to function as an integrated housing and I/O device and one or more sensors obscured by a panel of the housing. The one or more sensors being configured to sense via the panel of the housing. The electronic device further includes a processing unit communicatively coupled to the one or more sensors and configured to interpret electrical signals generated by the one or more sensors. One or more output devices are communicatively coupled to the processing unit and configured to provide an output in response to the one or more sensors generating an electrical signal.

Abstract: Analyte monitoring device calibration is described. A calibration system generates calibration results for multiple analyte monitoring devices during a calibration evaluation process. To do so, the calibration system implements a calibration board that includes a single ground electrode shared by, but not physically connected to, the multiple analyte monitoring devices. An input voltage is applied to an analyte-sensing element of each of the multiple analyte monitoring devices. Analyte-sensing elements and the common ground electrode are placed into/in contact with a reference bath that includes a known concentration of an analyte to be measured. The input voltage causes each analyte-sensing element to generate an electrical current that is indicative of the reference bath analyte concentration.

Abstract: Systems and methods facilitate sensing and tallying defecation events of subjects, such as participants in clinical trials for treatments for treating digestive diseases, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and chronic constipation. Systems and methods may also be used by individual patients for sensing and tallying defecation events, and resulting data may be reviewed by a healthcare provider when evaluating patient gastrointestinal health and/or treatments.

Abstract: There are provided systems, devices and methods for operating a housing for an electronic device as an input/output (I/O) device. In one embodiment, an electronic device includes a housing configured to function as an integrated housing and I/O device and one or more sensors obscured by a panel of the housing. The one or more sensors being configured to sense via the panel of the housing. The electronic device further includes a processing unit communicatively coupled to the one or more sensors and configured to interpret electrical signals generated by the one or more sensors. One or more output devices are communicatively coupled to the processing unit and configured to provide an output in response to the one or more sensors generating an electrical signal.

Abstract: The present disclosure describes a multi-analyte sensor system. The system includes a first sensor with a first enzyme for a first analyte, a second sensor with a second enzyme for a second analyte different from the first analyte, a potentiostat, a memory, and a processor communicatively coupled to the memory. The potentiostat applies a first voltage to the first sensor to cause a first current to flow through the first sensor and applies a second voltage to the second sensor to cause a second current to flow through the second sensor. The processor determines, based on the first current, a level of the first analyte and determines, based on the second current, a level of the second analyte.

Abstract: The present disclosure describes a multi-analyte sensor system that detects wear location. The system includes a first sensor, a second sensor, a memory, and a processor communicatively coupled to the memory. The first sensor produces a first signal stream indicating a level of a first analyte, and the second sensor produces first physiological data. The processor determines, based on the first signal stream and the first physiological data, a wear location of the first sensor and makes an adjustment related to at least one of the first sensor or the first signal stream based on the wear location of the first sensor.

Abstract: The present disclosure describes a multi-analyte sensor system that detects artifacts using multiple analytes. According to an embodiment, the multi-analyte sensor system includes a first analyte sensor, a second analyte sensor, and a sensor electronics module. The first analyte sensor produces a first analyte signal stream indicating a level of a first analyte. The second analyte sensor produces a second analyte signal stream indicating a level of a second analyte different from the first analyte. The sensor electronics module detects, based on the first analyte signal stream and the second analyte signal stream, at least one of a compression event or a dip and recover event and in response to detecting at least one of the compression event or the dip and recover event, make an adjustment related to at least one of the first analyte sensor or the first analyte signal stream based on the event.

Abstract: Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo are provided herein. In some examples, a device includes an indwelling sensor and sensor electronics. The sensor may include a substrate; a first electrode disposed on the substrate; an ionophore disposed on the substrate to selectively transport the target ion to or within the first electrode; and a second electrode disposed on the substrate. The sensor electronics is configured to generate a signal corresponding to an electromotive force which is at least partially based on a potential difference that is generated between the first electrode and the second electrode responsive to the ionophore transporting the target ion to the first electrode.

Abstract: Disclosed herein are systems and methods for a continuous analyte monitoring system for measuring a concentration of a first analyte and concentration of a second analyte in a host. One such system utilizes a working electrode and a reference electrode to measure glucose concentration and oxygen concentration in bodily fluid of a host. The system includes a sensor control circuit that applies a first bias condition to the sensor to measure a first signal generated by the sensor indicative of a concentration of the first analyte. The sensor control circuit also applies a second bias condition to the sensor to measure a second signal generated by the sensor indicative of a concentration of a second analyte at the host.

Abstract: Multi-function masks are presented including: a mask body forming a chamber, where the mask body includes an inner surface, an outer surface, an edge portion, a first intake portion, a second intake portion, a third intake portion, and an exhaust outlet portion, where the first intake portion passes filtered ambient air, where the second intake portion passes filtered and vaporized air, and where the third intake portion passes any of a fluid or a pressurized gas; a flexible contact portion positioned along the edge portion of the mask body for tightly contacting the mask body to a face when worn; and a filter unit positioned along the outer surface of the mask body for providing filtered ambient air to the first and second intake portions and for filtering exhaust air from the exhaust outlet portion.

Abstract: An electrochemical system includes fuel cell or electrolyzer modules, and a skid supporting the modules.

Abstract: An apparatus includes an analyte sensor, a memory, and a processor. The processor monitors, using the analyte sensor, an analyte of a patient during a time period to obtain measured analyte data for the analyte and monitors other measured sensor data indicative of a physiological state of the patient during the time period. The processor also determines, based on the physiological state of the patient during the time period, expected analyte data for the analyte and determines a correction factor based on the expected analyte data and the measured analyte data. The correction factor is indicative of an error in calibration of the analyte sensor. The processor also determines whether recalibration of the analyte sensor is possible. If recalibration is possible, the processor recalibrates the analyte sensor based on the correction factor, and if recalibration is not possible, the processor recommends, to the patient, to replace the analyte sensor.

Abstract: There are provided systems, devices and methods for operating a housing for an electronic device as an input/output (I/O) device. In one embodiment, an electronic device includes a housing configured to function as an integrated housing and I/O device and one or more sensors obscured by a panel of the housing. The one or more sensors being configured to sense via the panel of the housing. The electronic device further includes a processing unit communicatively coupled to the one or more sensors and configured to interpret electrical signals generated by the one or more sensors. One or more output devices are communicatively coupled to the processing unit and configured to provide an output in response to the one or more sensors generating an electrical signal.

Abstract: There are provided systems, devices and methods for operating a housing for an electronic device as an input/output (I/O) device. In one embodiment, an electronic device includes a housing configured to function as an integrated housing and I/O device and one or more sensors obscured by a panel of the housing. The one or more sensors being configured to sense via the panel of the housing. The electronic device further includes a processing unit communicatively coupled to the one or more sensors and configured to interpret electrical signals generated by the one or more sensors. One or more output devices are communicatively coupled to the processing unit and configured to provide an output in response to the one or more sensors generating an electrical signal.

Abstract: An augmented analyte monitoring system is described. The augmented analyte monitoring system includes a wearable analyte monitoring device that includes a transmitter and an analyte sensor to obtain analyte data of a user, and an analyte augmentation wearable that includes one or more sensors (e.g., physical and/or biochemical sensors) to obtain additional physiological data for augmenting the analyte data of the user. The analyte augmentation wearable is communicably coupled to the wearable analyte monitoring device. The augmented analyte monitoring system further includes a sensor hub implemented at a computing device to obtain a data packet containing both the analyte data and the additional physiological data from at least one of the wearable analyte monitoring device or the analyte augmentation wearable, and augment the analyte data by storing the analyte data in association with the additional physiological data.

Abstract: There are provided systems, devices and methods for operating a housing for an electronic device as an input/output (I/O) device. In one embodiment, an electronic device includes a housing configured to function as an integrated housing and I/O device and one or more sensors obscured by a panel of the housing. The one or more sensors being configured to sense via the panel of the housing. The electronic device further includes a processing unit communicatively coupled to the one or more sensors and configured to interpret electrical signals generated by the one or more sensors. One or more output devices are communicatively coupled to the processing unit and configured to provide an output in response to the one or more sensors generating an electrical signal.

Abstract: A processor collecting advertisement (ad) events of a user using a mobile device, such as a mobile phone or eyewear, parsing the ad events from the mobile device, and generating an ad receptivity profile on the granularity of a user identification (ID) and an hour of day. In one example, the processor computes the percentage of ad time watched by the individual user, such as on an hourly basis, and by monitoring a click-through rate (CTR) of the respective user as a measure for user ad receptivity. The processor adjusts an ad allocation/ad load on a per user basis according the user level ad receptivity profile, resulting in dynamically providing ads on the mobile device display when a user is active and receptive viewing the ads.

Abstract: A processor having a performance engine tracking user engagement of advertisement (ad) events using a mobile device, such as a mobile phone or eyewear, to generate a user level ad receptivity profile. In one example, the processor tracks both the percentage of ad time watched by the individual user, such as on an hourly basis, and ad engagement such as by monitoring a click-through rate (CTR) of the respective user as a measure for user ad receptivity. The processor downloads data from the performance engine to a server processor, and the server processor adjusts an ad allocation/ad load on a per user basis according the user level ad receptivity profile. The server processor dynamically provides ads on the mobile device display when a user is active and receptive viewing the ads.

Abstract: The present disclosure relates generally to systems and processes for assessing and differentiating asthma and chronic obstructive pulmonary disease (COPD) in a patient, and more specifically to computer-based systems and processes for providing a predicted diagnosis of asthma and/or COPD. In accordance with one or more examples, a computing system receives a set of patient data corresponding to a first patient and determines whether the set of patient data satisfies a set of one or more data-correlation criteria. If the set of one or more data-correlation criteria are satisfied, the computing system applies a first diagnostic model to the set of patient data and determines a first predicted diagnosis of asthma and/or COPD. If the set of one or more data-correlation criteria are not satisfied, the computing system applies a second diagnostic model to the set of patient data and determines a second predicted diagnosis of asthma and/or COPD.