Patents by Inventor Nicholas W. MORRELL

Nicholas W. MORRELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC USE OF BONE MORPHOGENETIC PROTEINS
    Publication number: 20240043485
    Abstract: The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
    Type: Application
    Filed: January 3, 2023
    Publication date: February 8, 2024
    Applicant: CAMBRIDGE ENTERPRISE LIMITED
    Inventors: Nicholas W. MORRELL, Wei LI, Paul D. UPTON
  • Therapeutic use of bone morphogenetic proteins
    Patent number: 11572396
    Abstract: The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: February 7, 2023
    Assignee: CAMBRIDGE ENTERPRISE LIMITED
    Inventors: Nicholas W. Morrell, Wei Li, Paul D Upton
  • THERAPEUTIC USE OF BONE MORPHOGENETIC PROTEINS
    Publication number: 20190359668
    Abstract: The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 28, 2019
    Applicant: CAMBRIDGE ENTERPRISE LIMITED
    Inventors: Nicholas W. Morrell, Wei Li, Paul D Upton
  • Therapeutic use of bone morphogenetic proteins
    Patent number: 10336800
    Abstract: The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: July 2, 2019
    Assignee: CAMBRIDGE ENTERPRISE LIMITED
    Inventors: Nicholas W. Morrell, Wei Li, Paul D Upton
  • THERAPEUTIC USE OF BONE MORPHOGENETIC PROTEINS
    Publication number: 20170209540
    Abstract: The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
    Type: Application
    Filed: July 9, 2015
    Publication date: July 27, 2017
    Inventors: Nicholas W. MORRELL, Wei LI, Paul D UPTON
  • THERAPEUTIC USE OF BONE MORPHOGENETIC PROTEINS
    Publication number: 20170121383
    Abstract: The invention relates to a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, and its use in the treatment of a vascular disease or a respiratory disease.
    Type: Application
    Filed: January 12, 2017
    Publication date: May 4, 2017
    Inventors: Nicholas W. MORRELL, Wei LI, Paul D. UPTON