Abstract: The present disclosure relates to methods of treating asthma, such as allergic asthma, neutrophilic asthma, mixed granulocytic asthma, and severe asthma. The present disclosure also relates to compounds for use in the treatment of asthma, as well as the use of such compounds in the manufacture of medicaments for the treatment of asthma.

Abstract: The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Abstract: The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Abstract: The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Abstract: In various implementations, a multi-axis GUI may be generated for rendition on a display. The GUI may be operable to navigate its focus through an array of selectable tiles along multiple axes. Each of the selectable tiles may be selectable to access a respective document from an online corpus. Based on directional input, the focus of the GUI may be shifted in a direction of the directional input from a first selectable tile to a second selectable tile of the array. Multiple distinct search queries may be formulated based on documents corresponding to the second tile and/or other tiles of the GUI. Sets of document(s) that are responsive to the multiple queries may be obtained and used to generate selectable tiles along axes of the GUI.

Abstract: A data processing apparatus maps input symbols to be communicated onto a predetermined number of sub-carrier signals of an Orthogonal Frequency Division Multiplexed (OFDM) symbol. The data processor includes an interleaver memory which reads-in the predetermined number of data symbols for mapping onto the OFDM sub-carrier signals. The interleaver memory reads-out the data symbols on to the OFDM sub-carriers to effect the mapping, the read-out being in a different order than the read-in, the order being determined from a set of addresses, with the effect that the data symbols are interleaved on to the sub-carrier signals. The set of addresses are generated from an address generator which comprises a linear feedback shift register and a permutation circuit.

Abstract: The present technology relates to a reception apparatus, a reception method, a transmission apparatus, and a transmission method that enable provision of an emergency warning service more suited to actual operation. Provided is a reception apparatus that includes a reception section and a demodulation section. The reception section receives a physical layer frame transported as a broadcast signal. The demodulation section demodulates physical layer signalling acquired from the physical layer frame and monitors whether or not emergency warning information has been transported on a basis of emergency warning notice information acquired as a result of the demodulation. In a case where the emergency warning notice information indicates that the emergency warning information has been transported, the reception apparatus starts up automatically. The present technology is applicable, for example, to a transport system for transporting a physical layer frame compliant with a DVB-T2 standard.

Abstract: A pin spanner tool for use with a driver having a center of rotation, the pin spanner having a driven arm, a floating arm, and a bolt connecting the driven arm and the floating arm, where the bolt has a center of rotation which is co-centric with the center of rotation of the driver.

Abstract: The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Abstract: The present disclosure relates to methods of treating asthma, such as allergic asthma, neutrophilic asthma, mixed granulocytic asthma, and severe asthma. The present disclosure also relates to compounds for use in the treatment of asthma, as well as the use of such compounds in the manufacture of medicaments for the treatment of asthma.

Abstract: A volatile liquid refueling apparatus, which includes a probe, and a receiver including a dual locking mechanism whereby said apparatus can be locked in either an open position or a closed position, and a safety lock which disables or enables access to the dual locking mechanism when manually.

Abstract: A tank portion defines a space therein and has an opening on one side. A foot portion is in a plate shape extending radially outward from a bottom end of the tank portion on the one side. A core plate covers the opening and has a base portion and a holder portion. The base portion is in an elongated rectangular plate shape having first and second long lateral sides and a short lateral side. The holder portion includes a first holder at the first long lateral side, a second holder at the second long lateral side, and a third holder at the short lateral side, each gripping the foot portion. All the first holder, the third holder, and the second holder are one piece continuously extending along the first long lateral side, the short lateral side, and the second long lateral side.

Abstract: A tool for installing circlips in a universal joint, the tool including a handle and a blade configured to hold a circlip, the blade further including a retaining device which holds the circlip until it can be installed on a universal joint.

Abstract: A data processing apparatus maps input symbols to be communicated onto a predetermined number of sub-carrier signals of an Orthogonal Frequency Division Multiplexed (OFDM) symbol. The data processor includes an interleaver memory which reads-in the predetermined number of data symbols for mapping onto the OFDM sub-carrier signals. The interleaver memory reads-out the data symbols on to the OFDM sub-carriers to effect the mapping, the read-out being in a different order than the read-in, the order being determined from a set of addresses, with the effect that the data symbols are interleaved on to the sub-carrier signals. The set of addresses are generated from an address generator which comprises a linear feedback shift register and a permutation circuit.

Abstract: A data processing apparatus maps input symbols to be communicated onto a predetermined number of sub-carrier signals of an Orthogonal Frequency Division Multiplexed (OFDM) symbol. The data processor includes an interleaver memory which reads-in the predetermined number of data symbols for mapping onto the OFDM sub-carrier signals. The interleaver memory reads-out the data symbols on to the OFDM sub-carriers to effect the mapping, the read-out being in a different order than the read-in, the order being determined from a set of addresses, with the effect that the data symbols are interleaved on to the sub-carrier signals. The set of addresses are generated from an address generator which comprises a linear feedback shift register and a permutation circuit.