Abstract: A method and system for enabling the determination of a position of a receiver within a space includes transmitting a beacon signal from each of a plurality of beacon devices located at different locations within the space. The beacon signal transmitted from each beacon device has a unique information component and may have a unique frequency pattern of multiple frequencies. Each beacon signal can be distinguishable from the beacon signals transmitted from any other of the beacon devices based on the combination of its unique information component and its unique frequency pattern. The beacon signals are received at a receiver. At the receiver, for each beacon signal of a working subset, time-delay information of the received beacon signal is determined and multilateration is applied to determine the position of the receiver based on the location of each beacon device of the working subset.

Abstract: A method and system for enabling the determination of a position of a receiver within a space includes transmitting a beacon signal from each of a plurality of beacon devices located at different locations within the space. The beacon signal transmitted from each beacon device has a unique information component and may have a unique frequency pattern of multiple frequencies. Each beacon signal can be distinguishable from the beacon signals transmitted from any other of the beacon devices based on the combination of its unique information component and its unique frequency pattern. The beacon signals are received at a receiver. At the receiver, for each beacon signal of a working subset, time-delay information of the received beacon signal is determined and multilateration is applied to determine the position of the receiver based on the location of each beacon device of the working subset.

Abstract: A method of transmitting data from a first device. The method comprises: at the first device, establishing a connection with a first one of a plurality of second devices and establishing a first virtual connection, the first virtual connection being between the first device and a third device through the first one of a plurality of second devices; and receiving details of a second virtual connection, the second virtual connection being between a fourth device and the third device through a second one of the plurality of second devices, the fourth device being connected to the first device. The method further comprises selecting one of said first or second virtual connections for transmission of a data packet to said third device and transmitting data to said third device using said selected connection.

Abstract: A method of determining suitable communication paths between a first device and a second device, the first device being connected to a plurality of third devices to which the second device is also connected. The method comprises, at the first device: for each of the third devices, obtaining first information indicating a characteristic of communications between the first device and the second device via the third device, obtaining second information associated with first data to be transmitted from the first device to the second device, and determining, based upon the first and second information, whether any of the third devices should receive the first data for communication of the first data to the second device.

Abstract: The present application relates to a method of providing connectivity to a vehicle. The method comprises, at a first device aboard the vehicle, establishing at least one first connection with at least one first network, the at least one first connection allowing communication with a second device remote from the first device, transmitting via the at least one first connection an allocation request to the second device, receiving via the at least one first connection an allocation response from the second device, the allocation response indicating a first authentication device from a plurality of authentication devices remote from the first device, and establishing a second connection with a network and authenticating the first device on the network using the first authentication device.

Abstract: The present application relates to a method of providing connectivity to a vehicle. The method comprises, at a first device aboard the vehicle, establishing at least one first connection with at least one first network, the at least one first connection allowing communication with a second device remote from the first device, transmitting via the at least one first connection an allocation request to the second device, receiving via the at least one first connection an allocation response from the second device, the allocation response indicating a first authentication device from a plurality of authentication devices remote from the first device, and establishing a second connection with a network and authenticating the first device on the network using the first authentication device.

Abstract: A method of transmitting data from a first device. The method comprises: at the first device, establishing a connection with a first one of a plurality of second devices and establishing a first virtual connection, the first virtual connection being between the first device and a third device through the first one of a plurality of second devices; and receiving details of a second virtual connection, the second virtual connection being between a fourth device and the third device through a second one of the plurality of second devices, the fourth device being connected to the first device. The method further comprises selecting one of said first or second virtual connections for transmission of a data packet to said third device and transmitting data to said third device using said selected connection.

Abstract: A method of determining suitable communication paths between a first device and a second device, the first device being connected to a plurality of third devices to which the second device is also connected. The method comprises, at the first device: for each of the third devices, obtaining first information indicating a characteristic of communications between the first device and the second device via the third device, obtaining second information associated with first data to be transmitted from the first device to the second device, and determining, based upon the first and second information, whether any of the third devices should receive the first data for communication of the first data to the second device.

Abstract: The APC tumor suppressor protein binds to .beta.-catenin, a protein recently shown to interact with Tcf/Lef transcription factors. Here, the gene encoding a Tcf family member that is expressed in colonic epithelium (hTcf-4) a was cloned and characterized. hTcf-4 transactivates transcription only when associated with .beta.-catenin. Nuclei of APC.sup.-/- colon carcinoma cells were found to contain a stable .beta.-catenin-hTCF-4 complex that was constitutively active, as measured by transcription of a Tcf reporter gene. Reintroduction of APC removed .beta.-catenin from hTcf4 and abrogated the transcriptional transactivation. Constitutive transcription of TCF target genes, caused by loss of APC function, may be a crucial event in the early transformation of colonic epithelium. It is also shown here that the products of mutant APC genes found in colorectal tumors are defective in regulating .beta.-catenin/Tcf-4 transcrpitional activation.

Abstract: The APC tumor suppressor protein binds to .beta.-catenin, a protein recently shown to interact with Tcf/Lef transcription factors. Here, the gene encoding a Tcf family member that is expressed in colonic epithelium (hTcf-4) was cloned and characterized. hTcf-4 transactivates transcription only when associated with .beta.-catenin. Nuclei of APC.sup.-/- colon carcinoma cells were found to contain a stable .beta.-catenin-hTCF-4 complex that was constitutively active, as measured by transcription of a Tcf reporter gene. Reintroduction of APC removed .beta.-catenin from hTcf4 and abrogated the transcriptional transactivation. Constitutive transcription of TCF target genes, caused by loss of APC function, may be a crucial event in the early transformation of colonic epithelium. It is also shown here that the products of mutant APC genes found in colorectal tumors are defective in regulating .beta.-catenin/Tcf-4 transcrpitional activation.

Abstract: A disc storage device for holding and storing discs such as computer floppy discs, compact discs, slides and the like. The device comprises a set of modules for holding the discs having a planar surface, four walls surrounding the planar surface holding means to prevent the disc from moving within the module and ejector means for easy removal of the disc from the module. The device may include 12 modules arrayed on an 81/2 by 11" one-piece plastic unit which may be inserted into a ring binder notebook or inserted as a rail file in a filing cabinet.