Abstract: A fluid dispensing system, fluid reservoir, refill container for refilling the fluid reservoir, and method of refilling the fluid reservoir are provided. The fluid dispensing system includes a refill connection port or nozzle to which a refill container is connected when refilling the fluid reservoir. The fluid reservoir includes a piston head and an actuator for moving the piston head in a first direction and in a second direction. When the piston head is moved in the first direction, the fluid within the fluid reservoir is pressurized, causing the fluid to be dispensed through an outlet of the fluid reservoir. When the piston head is moved in the second direction, a vacuum is created within the fluid reservoir that draws fluid, from the refill container, into the fluid reservoir. The fluid dispensing system includes a valve to enable multiple refill containers to be coupled to the nozzle and/or the refill connection port.