Abstract: Provided herein are novel docking peptides and antibody-based drug conjugates that include such docking peptides. In embodiments, the subject docking peptide allows for the controlled attachment of one or more drug moieties and a tumor targeting moiety that allows for the targeting of the drug moiety to the tumor microenvironment. In some embodiments, the antibody-based drug conjugates provided herein advantageously allows for enhanced targeted delivery of a drug payload having a controlled drug-to-antibody ratio (DAR) to a target site.

Abstract: Systems, methods, and computer-readable media storing instructions for determining cross-track error of an aircraft on a taxiway are disclosed herein. The disclosed techniques capture electronic images of a portion of the taxiway using cameras or other electronic imaging devices mounted on the aircraft, pre-process the electronic images to generate regularized image data, apply a trained multichannel neural network model to the regularized image data to generate a preliminary estimate of cross-track error relative to the centerline of the taxiway, and post-process the preliminary estimate to generate an estimate of cross-track error of the aircraft. Further embodiments adjust a GPS-based location estimate of the aircraft using the estimate of cross-track error or adjust the heading of the aircraft based upon the estimate of cross-track error.

Abstract: Systems, methods, and computer-readable media storing instructions for determining cross-track error of an aircraft on a taxiway are disclosed herein. The disclosed techniques capture electronic images of a portion of the taxiway using cameras or other electronic imaging devices mounted on the aircraft, pre-process the electronic images to generate regularized image data, apply a trained multichannel neural network model to the regularized image data to generate a preliminary estimate of cross-track error relative to the centerline of the taxiway, and post-process the preliminary estimate to generate an estimate of cross-track error of the aircraft. Further embodiments adjust a GPS-based location estimate of the aircraft using the estimate of cross-track error or adjust the heading of the aircraft based upon the estimate of cross-track error.

Abstract: A material capable of luminescence comprising a polymer or oligomer and an organometallic group, wherein the polymer or oligomer is at least partially conjugated and the organometallic group is covalently bound to the polymer or oligomer and at least one of the nature, location, and proportion of the polymer or oligomer and of the organometallic group in the material are selected so that the luminescence predominantly is phosphorescence.

Abstract: A material capable of luminescence comprising a polymer or oligomer and an organometallic group, wherein the polymer or oligomer is at least partially conjugated and the organometallic group is covalently bound to the polymer or oligomer and at least one of the nature, location, and proportion of the polymer or oligomer and of the organometallic group in the material are selected so that the luminescence predominantly is phosphorescence.