Abstract: A separating system, for example for separating material from a suspension such as a biological suspension, is disclosed herein. The system comprises a separation vessel arranged to enable the formation of a cyclone therewithin. For example, the separation vessel may be at least partially conical in shape for enabling the formation of a cyclone therewithin. The separation vessel comprises a fluid inlet, an underflow outlet, a first overflow outlet for removing fluid from a first region inside the separation vessel, and a second overflow outlet for removing fluid from a second region inside the separation vessel.