Patents by Inventor Nick Newton

Nick Newton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HAV detection
    Patent number: 10865454
    Abstract: Methods for detecting HAV in a biological sample are provided, comprising amplifying a target nucleic acid comprising the sequence of HAV in a reaction mixture. The reaction mixture comprises a biological sample which may contain the target nucleic acid and set of oligonucleotides. The invention also provides kits for the detection of HAV.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: December 15, 2020
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Hermann Leying, Ning Lu, Nick Newton, Andreas Wolfelschneider, Karen Young, Dirk Zimmermann
  • HAV DETECTION
    Publication number: 20190010562
    Abstract: Methods for detecting HAV in a biological sample are provided, comprising amplifying a target nucleic acid comprising the sequence of HAV in a reaction mixture. The reaction mixture comprises a biological sample which may contain the target nucleic acid and set of oligonucleotides. The invention also provides kits for the detection of HAV.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 10, 2019
    Inventors: Hermann Leying, Ning Lu, Nick Newton, Andreas Wolfelschneider, Karen Young, Dirk Zimmermann
  • HAV detection
    Patent number: 10100374
    Abstract: Methods for detecting HAV in a biological sample are provided, comprising amplifying a target nucleic acid comprising the sequence of HAV in a reaction mixture. The reaction mixture comprises a biological sample which may contain the target nucleic acid and set of oligonucleotides. The invention also provides kits for the detection of HAV.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: October 16, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Hermann Leying, Ning Lu, Nick Newton, Andreas Wolfelschneider, Karen Young, Dirk Zimmermann
  • Non-invasive early detection of solid organ transplant rejection by quantitative analysis of mixtures by deep sequencing of HLA gene amplicons using next generation systems
    Patent number: 9752189
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient. The invention further comprises a method of detecting the presence of maternal cells in a blood sample of an offspring.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 5, 2017
    Assignees: Roche Molecular Systems, Inc., The Scripps Research Institute
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Nancy Schoenbrunner, Alison Tsan, Daniel Salomon
  • NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF HLA GENE AMPLICONS
    Publication number: 20160017421
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection and acute dysfunction—no rejection condition by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient.
    Type: Application
    Filed: November 3, 2014
    Publication date: January 21, 2016
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Daniel Salomon, Nancy Shoenbrunner, Alison Tsan
  • METHOD OF DETERMINING THE FRACTION OF FETAL DNA IN MATERNAL BLOOD USING HLA MARKERS
    Publication number: 20150203914
    Abstract: The invention comprises a method of determining the fraction of fetal DNA in maternal blood or plasma using HLA locus wherein the maternal and fetal HLA alleles are detected and quantified by clonal or digital methods.
    Type: Application
    Filed: May 9, 2014
    Publication date: July 23, 2015
    Applicant: Roche Molecular Systems
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Nancy Schoenbrunner, Alison Tsan
  • NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF MIXTURES BY DEEP SEQUENCING OF HLA GENE AMPLICONS USING NEXT GENERATION SYSTEMS
    Publication number: 20140336056
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient. The invention further comprises a method of detecting the presence of maternal cells in a blood sample of an offspring.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 13, 2014
    Applicants: Roche Molecular Systems, The Scripps Research Institute
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Nancy Schoenbrunner, Alison Tsan, Daniel Salomon
  • HAV detection
    Publication number: 20140170638
    Abstract: Methods for detecting HAV in a biological sample are provided, comprising amplifying a target nucleic acid comprising the sequence of HAV in a reaction mixture. The reaction mixture comprises a biological sample which may contain the target nucleic acid and set of oligonucleotides. The invention also provides kits for the detection of HAV.
    Type: Application
    Filed: November 22, 2013
    Publication date: June 19, 2014
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Hermann Leying, Ning Lu, Nick Newton, Andreas Wolfelschneider, Karen Young, Dirk Zimmermann
  • Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids
    Publication number: 20070072211
    Abstract: The present invention provides methods, compositions, and kits for quantification and identification of target nucleic acid sequences, either in pure solutions or from mixtures of various nucleic acids. In other aspects, the invention provides compositions and methods for HCV genotyping.
    Type: Application
    Filed: June 23, 2006
    Publication date: March 29, 2007
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Nick Newton, Stephen Will