Patents by Inventor Nick Nikolaides

Nick Nikolaides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-(2-imidazolinylamino)-benzimidazole derivatives, their preparation and their use as .alpha.-adrenoceptor agonists with improved metabolic stability
    Patent number: 6486190
    Abstract: Benzimidazole compounds having the generic structure: are used to treat alpha-2 mediated disorders, including nasal congestion, glaucoma, asthma, migraine, and diarrhea.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: November 26, 2002
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Nick Nikolaides, Sheri Ann Gilbert, Michael Gazda, Roy Lee Dobson, Charles Andrew III Cruze
  • Fused cycloalkylimidazopyridines
    Patent number: 5886006
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: March 23, 1999
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Fused cycloalkylimidazopyridines
    Patent number: 5648516
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells, their pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds are disclosed.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 15, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Imidazo[4,5-c]pyridin-4-amine intermediates
    Patent number: 5644063
    Abstract: Imidazo[4,5-c]pyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis involving the use of such compounds.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 1, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Kyle J. Lindstrom, Nick Nikolaides
  • Intermediate compounds of fused cycloalkylimidazopyridines
    Patent number: 5627281
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines and their intermediate compounds are described. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating vital infections involving the use of such compounds.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: May 6, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Imidazo[4,5-C]pyridin-4-amines
    Patent number: 5494916
    Abstract: Imidazo[4,5-c]pyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis involving the use of such compounds.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: February 27, 1996
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Kyle J. Lindstrom, Nick Nikolaides
  • Intermediates for imidazo[4,5-c]pyridin-4-amines
    Patent number: 5446153
    Abstract: Imidazo[4,5-c]pyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis involving the use of such compounds.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: August 29, 1995
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Kyle J. Lindstrom, Nick Nikolaides
  • Fused cycloalkylimidazopyridines as inducer of interferon .alpha. biosynthesis
    Patent number: 5444065
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: August 22, 1995
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Process for preparing quinoline amines
    Patent number: 5395937
    Abstract: A process that involves reacting a 3-nitroquinoline-2,4-disulfonate with an amine or a substituted amine to selectively aminate at the 4-position to yield 1H-imidazo[4,5-c]quinolin-4-amines is disclosed.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: March 7, 1995
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, Kyle J. Lindstrom
  • Fused cycloalkylimidazopyridines
    Patent number: 5352784
    Abstract: [6,7]-propylene-, -butylene- or -pentylene-fused imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: October 4, 1994
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster