Abstract: A pharmaceutical vial, container assembly, system and method. The vial can include a hollow body, a first passage, a second passage, a first temporary closure sealing the first passage, and a second temporary closure sealing the second passage. A diluent container can include a first connector to connect the diluent container and vial in fluid communication for mixing an active pharmaceutical ingredient with a diluent. An infusion set can include a second connector to connect the infusion set and vial in fluid communication, and a delivery device. The method can include the steps of connecting the diluent container to the first temporary closure of the vial, transferring a diluent from the diluent container into the vial, reconstituting an active pharmaceutical ingredient with the diluent to form a solution, connecting the delivery device to the second temporary closure, and administering the solution through the delivery device into a patient.

Abstract: The present invention relates to a process for the biocatalytic, enantioselective production of a ?-amino acid precursor from an optionally substituted dihydrouracil using a hydantoinase and/or a dihydropyrimidinase, a process for producing a ?-amino acid from said precursor, a hydantoinase and its use in said process for the biocatalytic production of a ?-amino acid precursor or a ?-amino acid, and a method for obtaining said hydantoinase.

Abstract: Protective structures that may be used in various protective gear items, such as helmets and the like. In some embodiments, the protective structure may comprise a layered structure having three distinct layers. The various layers may be selected, arranged, and configured to provide for improved protection at multiple velocities, such as high velocity impacts and low velocity impacts. Some embodiments may also, or alternatively, be configured to provide improved protection and/or durability for multiple impacts at the same portion of the helmet over time.

Abstract: The present invention relates to a process for the biocatalytic, enantioselective production of a ?-amino acid pre-cursor from an optionally substituted dihydrouracil using a hydantoinase and/or a dihydropyrimidinase, a process for producing a ?-amino acid from said precursor, a hydantoinase and its use in said process for the biocatalytic production of a ?-amino acid pre-cursor or a ?-amino acid, and a method for obtaining said hydantoinase.

Abstract: The present invention relates to a method for the enzymatic hydroamination of C—C double bonds catalyzed by enzymes structurally and/or functionally related to phenylalanine ammonia lyase (PAL) isolated from microorganisms of Petroselinum crispum, Rhodoturula glutinis and/or functional active derivatives thereof.