Patents by Inventor Nick V. Grishin

Nick V. Grishin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autophagy-inducing peptide analogs
    Patent number: 10300106
    Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Beclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: May 28, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Beth C. Levine, Sanae Shoji-Kawata, Nick V. Grishin, Lisa N. Kinch, Olivier Lichtarge, Angela D. Wilkins
  • Autophagy-Inducing Peptide Analogs
    Publication number: 20150359840
    Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Belclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.
    Type: Application
    Filed: September 3, 2015
    Publication date: December 17, 2015
    Applicants: BAYLOR COLLEGE OF MEDICINE, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Beth C. Levine, Sanae Shoji-Kawata, Nick V. Grishin, Lisa N. Kinch, Olivier Lichtarge, Angela D. Wilkins
  • Autophagy-inducing peptide analogs
    Patent number: 8802633
    Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 residues 269-279 immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said residues may be substituted, R1 and R2 do not naturally flank the Belclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: August 12, 2014
    Assignees: Board of Regents, The University of Texas System, Baylor College of Medicine
    Inventors: Beth C. Levine, Sanae Shoji-Kawata, Olivier Lichtarge, Angela D. Wilkins, Nick V. Grishin, Lisa N. Kinch
  • GHRELIN O-ACYLTRANSFERASE (GOAT) BIOCHEMICAL ASSAY
    Publication number: 20090170141
    Abstract: Ghrelin is acylated ghrelin O-acyltransferase. Ghrelin O-acyltransferase assays comprise contacting a mixture of ghrelin and recombinant ghrelin O-acyltransferase with an agent; and detecting a resultant decrease in acylation of the ghrelin by the acyltransferase.
    Type: Application
    Filed: December 29, 2007
    Publication date: July 2, 2009
    Inventors: Michael S. Brown, Joseph L. Goldstein, Nick V. Grishin, Jing Yang
  • Ghrelin o-acyltransferase (GOAT) biochemical assay
    Patent number: 7544466
    Abstract: Ghrelin is acylated by ghrelin O-acyltransferase. Ghrelin O-acyltransferase assays comprise contacting a mixture of ghrelin and recombinant ghrelin O-acyltransferase with an agent; and detecting a resultant decrease in acylation of the ghrelin by the acyltransferase.
    Type: Grant
    Filed: December 29, 2007
    Date of Patent: June 9, 2009
    Assignee: Board of Regents, The University of Texas System
    Inventors: Michael S. Brown, Joseph L. Goldstein, Nick V. Grishin, Jing Yang