Patents by Inventor Nick Van Gastel

Nick Van Gastel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING ACUTE MYELOID LEUKEMIA
    Publication number: 20230136218
    Abstract: The disclosure relates to compositions, methods, and kits for treating leukemia, specifically acute myeloid leukemia, in a subject.
    Type: Application
    Filed: September 23, 2020
    Publication date: May 4, 2023
    Applicants: President and Fellows of Harvard College, The General Hospital Corporation, The General Hospital Corporation
    Inventors: Nick Van Gastel, David T. Scadden
  • ALDH3A2 INHIBITION AND FERROPTOSIS INDUCTION FOR CANCER THERAPY
    Publication number: 20230000896
    Abstract: Disclosed herein are methods and compositions for inhibiting Aldh3a2 expression and activity to improve leukemia outcomes. Aldh3a2 depletion results in iron-dependent oxidative cell death of leukemia cells while sparing normal hematopoiesis.
    Type: Application
    Filed: December 9, 2020
    Publication date: January 5, 2023
    Inventors: David T. Scadden, Rushdia Yusuf, Nick Van Gastel, Azeem S. Sharda, Borja Saez, Shrikanta Chattopadhyay, Vasanthi S. Viswanathan
  • METHODS AND COMPOSITIONS FOR TREATING ACUTE MYELOID LEUKEMIA
    Publication number: 20210177880
    Abstract: The disclosure relates to compositions, methods, and kits for treating leukemia, specifically acute myeloid leukemia, in a subject, and for detecting chemoresistant acute myeloid leukemic cells.
    Type: Application
    Filed: October 31, 2018
    Publication date: June 17, 2021
    Inventors: Nick Van Gastel, David T. Scadden, Toshihiko Oki, Amir Schajnovitz