Patents by Inventor Nickolas Serniuck

Nickolas Serniuck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240109870
    Abstract: The present application relates to compounds of Formula I comprising an antibody binding domain (ABD) comprising a hapten that binds to an antibody in a subject, the antibody comprising a hapten binding site, an antibody labelling domain (ALD) comprising a functional group that forms a covalent bond with an amino acid in the antibody that is proximal to the hapten binding site and the formation of the covalent bond results in elimination of the ABD and either a target binding domain (TBD) or a detection moiety domain (DMD), each domain being optionally connected with independently selected linkers. The present application also includes methods and uses of the compounds, for example, for immune recognition of target cells by recruited labelled antibodies.
    Type: Application
    Filed: October 25, 2023
    Publication date: April 4, 2024
    Applicant: McMaster University
    Inventors: Anthony Rullo, Jonathan Bramson, Yonghong Wan, Benjamin Lake, Nickolas Serniuck