Abstract: A medical device securement system includes a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, a first array of microneedles projecting from a tissue contacting surface of the first section and a second array of microneedles projecting from a tissue contacting surface of the second section, a retention device provided on the main body for receiving and engaging the medical device, wherein the first section comprises a first base defining the tissue contacting surface and a closure member hingedly articulated relative to the first base between a closed position defining an enclosure between the first base and the closure member in which the retention device is located and in which the medical device may be at least partially contained, and an open position permitting access to the enclosure.

Abstract: The present invention provides a microneedle patch application system designed to facilitate the simple and expeditious deployment of a microneedle patch onto a tissue substrate such as the skin, for drug delivery or other applications, the system including a microneedle patch including arrays of opposing microneedles and an applicator operable to deploy the patch onto the tissue substrate by displacing the patch from an undeployed to a deployed state.

Abstract: A stabilisation system for securing a medical device such as a catheter to tissue, in particular skin, the stabilisation system comprising a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, each section including an array of microneedles extending from a tissue contacting surface of the body and which penetrate the skin in response to the above displacement, the stabilisation system further comprising a closure member displaceable between an open position exposing a retention zone on the body and a closed position at least partially occluding the retention zone, within which retention zone the catheter or other medical device may be captured.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.

Abstract: The present invention provides a stabilisation system for securing a medical device such as a catheter to tissue, in particular skin, the stabilisation system comprising a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, each section including an array of microneedles extending from a tissue contacting surface of the body and which penetrate the skin in response to the above displacement, the stabilisation system further comprising a closure member displaceable between an open position exposing a retention zone on the body and a closed position at least partially occluding the retention zone, within which retention zone the catheter or other medical device may be captured.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.

Abstract: Technologies are generally provided for a spinal fusion device to achieve interbody fusion and maintain intervertebral spacing. The spinal fusion device includes at least two wedge-shaped intervertebral implants (IVIs) configured to be inserted between adjacent vertebrae, such that a thin end of each IVI is positioned toward a midline of the vertebrae, and a thick end of each IVI is positioned substantially flush with outer surfaces of the vertebrae. A lower surface of a superior vertebral body and an upper surface of an adjacent inferior vertebral body are resected to accommodate the IVIs, and a portion of an intervertebral disc (IVD) is also removed to facilitate insertion of the IVIs. The IVIs are inserted in substantially opposite positions to each other between the vertebrae, and an interconnecting member is inserted to connect the IVIs. The interconnecting member passes through residual IVD to stabilize the IVIs in position between the vertebrae.

Abstract: Technologies are generally provided for a tissue removal device for removing tissue protrusions extending from a wall of intestines. The tissue removal device may be a bell shaped tube configured to slide over an inflamed diverticulum that has been inverted to extend into interior space of the colon. The tissue removal device run be slid over the inverted diverticulum with a portion of the tissue removal device having a widest diameter oriented near the colon wall and a portion having a narrowest diameter oriented near a tip of the diverticulum. A pressure gradient may be induced along the walls of the tissue removal device such that the point of highest pressure at the narrowest opening may cause the walls of the diverticulum to be pinched together to induce necrosis and removal of the diverticulum, while promoting healing of the colon walls over the region of decreasing pressure.

Abstract: Technologies are generally provided for a spinal fusion device to achieve interbody fusion and maintain intervertebral spacing. The spinal fusion device includes at least two wedge-shaped intervertebral implants (IVIs) configured to be inserted between adjacent vertebrae, such that a thin end of each IVI is positioned toward a midline of the vertebrae, and a thick end of each IVI is positioned substantially flush with outer surfaces of the vertebrae. A lower surface of a superior vertebral body and an upper surface of an adjacent inferior vertebral body are resected to accommodate the IVIs, and a portion of an intervertebral disc (IVD) is also removed to facilitate insertion of the IVIs. The IVIs are inserted in substantially opposite positions to each other between the vertebrae, and an interconnecting member is inserted to connect the IVIs. The interconnecting member passes through residual IVD to stabilize the IVIs in position between the vertebrae.

Abstract: Technologies are generally provided for a meniscal repositioning device to achieve at least a partial unloading of an ipsilateral tibiofemoral articulation. The device may include at least a shortening component and a fixation component. The shortening component may be configured to reduce a functional length of a meniscal root of a meniscus through an introduction of a targeted and strategic deviation in the device associated with an accommodation of the meniscal root. The deviation may cause a path of at least one portion of the meniscus to be altered, further causing the meniscus to be drawn inward towards a midline of a knee to induce a distraction force in a medial or lateral compartment of the knee between menisci. The fixation component may affix the shortening component to a portion of a tibia adjacent to the meniscal root or an anterior and/or posterior portion of the meniscal root.

Abstract: Technologies are generally provided for an attachment device to achieve pelvic fracture reduction and stabilization. An example attachment device may include two or more screws coupled together in succession to generate a reduction force when inserted through bony tissue. Each screw may have a hollow center, and a guide wire defining a linear or curvilinear path through bony tissue may be configured to pass through the center of the screws. Successive screw segments may exhibit increasing thread pitch to permit generation of a reduction force across multiple fracture planes. Each screw segment may vary in length, diameter, and pitch to enable customization of a configuration of the attachment device according to anatomical needs. Distal and proximal ends of each screw segment may be configured such that multiple rotational degrees of freedom of successive screws may be permitted about axes forming tangents with a longitudinal axis of the guide wire.

Abstract: Technologies are generally provided for a medical sponge configured to reduce a temperature at a surgical site. Endothermic reactants may be incorporated with the medical sponge to reduce a temperature at the surgical site in response to absorption of fluids. The sponge may be placed at a surgical site, and as the sponge absorbs fluids, the endothermic reactants may become hydrated. Hydration of the endothermic elements may induce an endothermic reaction, resulting in reduction of a temperature of the surrounding surgical site. The endothermic elements may be inserted within semi-permeable pouches that may be layered with the sponge. Additionally, endothermic elements may be inserted within hollow semi-permeable fibers and woven together to form the sponge. Hemostatic agents, antimicrobial agents, and analgesics may also be integrated with the medical sponge to prevent and treat other conditions experienced at the surgical site such as inflammation, pain, and infection.

Abstract: Technologies are generally provided for a tissue removal device for removing tissue protrusions extending from a wall of intestines. The tissue removal device may be a bell shaped tube configured to slide over an inflamed diverticulum that has been inverted to extend into interior space of the colon. The tissue removal device run be slid over the inverted diverticulum with a portion of the tissue removal device having a widest diameter oriented near the colon wall and a portion having a narrowest diameter oriented near a tip of the diverticulum. A pressure gradient may be induced along the walls of the tissue removal device such that the point of highest pressure at the narrowest opening may cause the walls of the diverticulum to be pinched together to induce necrosis and removal of the diverticulum, while promoting healing of the colon walls over the region of decreasing pressure.