Patents by Inventor Nico Boon
Nico Boon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230346670Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from hemolysin, N-acetyl-D-glucosamine, ?-D-lactose, D-(+)-trehalose or D-(+)-raffinose and mixtures thereof; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: ApplicationFiled: September 30, 2021Publication date: November 2, 2023Inventors: Wim TEUGHELS, Tim VERSPECHT, Kristel BERNAERTS, Marc QUIRYNEN, Nico BOON, Carlo DAEP, James MASTERS
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Patent number: 11419806Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myo-inositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: GrantFiled: May 29, 2019Date of Patent: August 23, 2022Assignee: Colgate-Palmolive CompanyInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Publication number: 20220257491Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-mannose, N-acetyl-D-mannosamine and mixtures thereof; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: ApplicationFiled: February 16, 2022Publication date: August 18, 2022Inventors: Wim TEUGHELS, Tim VERSPECHT, Kristel BERNAERTS, Marc QUIRYNEN, Nico BOON, Carlo DAEP, James MASTERS
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Patent number: 11241474Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.Type: GrantFiled: November 9, 2018Date of Patent: February 8, 2022Assignees: Colgate-Palmolive Company, Katholieke Universiteit Leuven, Universiteit GentInventors: Hansruedi Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Publication number: 20210251862Abstract: The present invention provides an oral care composition comprising a carboxylic acid of the formula: wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and/or re-establishing a healthy oral microflora.Type: ApplicationFiled: February 9, 2021Publication date: August 19, 2021Applicants: Colgate-Palmolive Company, Katholieke Universiteit Leuven, Universiteit GentInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Patent number: 10945932Abstract: The present invention provides an oral care composition comprising a carboxylic acid of the formula (I) wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and/or re-establishing a healthy oral microflora.Type: GrantFiled: December 27, 2013Date of Patent: March 16, 2021Assignees: Colgate-Palmolive Company, Katholieke Universiteit LeuvenInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Publication number: 20190336428Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myo-inositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: ApplicationFiled: May 29, 2019Publication date: November 7, 2019Applicants: Colgate-Palmolive Company, KATHOLIEKE UNIVERSITEIT LEUVEN, UNIVERSITEIT GENTInventors: Hansruedi STETTLER, Wim TEUGHELS, Marc QUIRYNEN, Nico BOON
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Patent number: 10328010Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myoinositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: GrantFiled: December 27, 2013Date of Patent: June 25, 2019Assignee: Colgate-Palmolive CompanyInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Patent number: 10307357Abstract: The disclosure relates to an oral care composition an effective amount of at least one C?1-4#191 (optionally hydroxylated) alkyl glycoside, e.g., ?-methyl-D-galactoside, wherein the glycoside promotes the growth of beneficial endogenous bacteria and negatively affects the growth of endogenous pathogenic strains of bacteria. The disclosure also relates to methods of use, methods of screening, and methods of manufacture of said oral care compositions.Type: GrantFiled: December 27, 2013Date of Patent: June 4, 2019Assignee: Colgate-Palmolive CompanyInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon, Gitte Loozen
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Publication number: 20190076351Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.Type: ApplicationFiled: November 9, 2018Publication date: March 14, 2019Applicant: Colgate-Palmolive CompanyInventors: Hansruedi STETTLER, Wim TEUGHELS, Marc QUIRYNEN, Nico BOON
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Patent number: 10159640Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.Type: GrantFiled: December 27, 2013Date of Patent: December 25, 2018Assignee: Colgate-Palmolive CompanyInventors: Hans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Publication number: 20160338932Abstract: The disclosure relates to an oral care composition an effective amount of at least one C?1-4#191 (optionally hydroxylated) alkyl glycoside, e.g., ?-methyl-D-galactoside, wherein the glycoside promotes the growth of beneficial endogenous bacteria and negatively affects the growth of endogenous pathogenic strains of bacteria. The disclosure also relates to methods of use, methods of screening, and methods of manufacture of said oral care compositions.Type: ApplicationFiled: December 27, 2013Publication date: November 24, 2016Inventors: Hans Stettler, Wim TEUGHELS, Marc QUIRYNEN, Nico Boon, Gitte LOOZEN
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Publication number: 20160338924Abstract: The present invention provides an oral care composition comprising a carboxylic acid of the formula (I) wherein: R1 is H, or is a substituted or unsubstituted alkyl group; and R2 is H, OH, or NH2; for use in: (a) selectively promoting, in an oral cavity: growth, metabolic activity or colonization of bacteria that have beneficial effects on oral health, relative to growth, metabolic activity or colonization of pathogenic oral bacteria; (b) selectively promoting, in an oral cavity, biofilm formation by bacteria that have beneficial effects on oral health, relative to biofilm formation by pathogenic oral bacteria; or (c) maintaining and/or re-establishing a healthy oral microflora.Type: ApplicationFiled: December 27, 2013Publication date: November 24, 2016Inventors: Hans Stettler, Wim TEUGHELS, Marc QUIRYNEN, Nico Boon
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Publication number: 20160324766Abstract: The present invention provides an oral care composition comprising: (a) a dipeptide of the formula Xaa1-Xaa2 or Xaa2-Xaa1; wherein Xaa1 is an amino acid with a polar uncharged side chain; and Xaa2 is selected from an amino acid with a hydrophobic side chain, an amino acid with a polar uncharged side chain, and proline; or (b) a dipeptide of the formula Xaa3-Xaa4 or Xaa4-Xaa3; wherein Xaa3 is an amino acid with a hydrophobic side chain; and Xaa4 is selected from an amino acid with a hydrophobic side chain and an amino acid with a charged side chain.Type: ApplicationFiled: December 27, 2013Publication date: November 10, 2016Inventors: Hans STETTLER, Wim TEUGHELS, Marc QUIRYNEN, Nico BOON
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Publication number: 20160317414Abstract: The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myoinositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.Type: ApplicationFiled: December 27, 2013Publication date: November 3, 2016Applicants: COLGATE-PALMOLIVE COMPANY, KATHOLIEKE UNIVERSITEIT LEUVEN, UNIVERSITEIT GENTInventors: Hans Stettler, Wim TEUGHELS, Marc QUIRYNEN, Nico Boon
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Patent number: 8603518Abstract: This invention relates to the use of hydroxybutyrate and poly hydroxybutyrate as components of animal feed or feed additives, as well as to compositions, feed additives and feed containing them. The inventors surprisingly found that hydroxybutyrate and poly-hydroxybutyrate, preferably 3-hydroxybutyrate and poly-3-hydroxybutyrate, have a great potential for use in animal feed for modulation of the gut flora. More precisely, it has been found that poly-3-hydroxybutyrate or a microbial strain capable for producing poly-3-hydroxybutyrate can be used as a potential growth promoter or gut flora modulator by releasing SCFA, preferably 3-hydroxy butyric acid, in the gut micro flora. Further, the inventors found that 3-hydroxybutyrate and poly-3-hydroxybutyrate have a great potential for suppressing or inhibiting pathogenic bacteria in the gastro intestinal tract, e.g. have a antimicrobial activity against strains of Vibrio, E. coli and Salmonella.Type: GrantFiled: May 1, 2007Date of Patent: December 10, 2013Assignee: Universiteit GentInventors: Nico Boon, Tom Defoirdt, Wim De Windt, Tom Van De Wiele, Willy Verstraete
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Patent number: 8454986Abstract: Silver nanoparticles associated with 20 to 80% by weight of a biocomponent of the genus Lactobacillus, said silver nanoparticles having a ratio of the average particle size to the specific surface area (BET) of from 0.015 to 0.Type: GrantFiled: January 2, 2009Date of Patent: June 4, 2013Assignee: Janssen Pharmaceutica N.V.Inventors: Wim De Windt, Mariane Van Wambeke, Willy Verstraete, Nico Boon
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Publication number: 20100272770Abstract: Silver nanoparticles associated with 20 to 80% by weight of a biocomponent of the genus Lactobacillus, said silver nanoparticles having a ratio of the average particle size to the specific surface area (BET) of from 0.015 to 0.Type: ApplicationFiled: January 2, 2009Publication date: October 28, 2010Inventors: Wim De Windt, Mariane Van Wambeke, Willy Verstraete, Nico Boon
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Publication number: 20100093860Abstract: This invention relates to the use of hydroxybutyrate and poly hydroxybutyrate as components of animal feed or feed additives, as well as to compositions, feed additives and feed containing them. The inventors surprisingly found that hydroxybutyrate and poly-hydroxybutyrate, preferably 3-hydroxybutyrate and poly-3-hydroxybutyrate, have a great potential for use in animal feed for modulation of the gut flora. More precisely, it has been found that poly-3-hydroxybutyrate or a microbial strain capable for producing poly-3-hydroxybutyrate can be used as a potential growth promoter or gut flora modulator by releasing SCFA, preferably 3-hydroxy butyric acid, in the gut micro flora. Further, the inventors found that 3-hydroxybutyrate and poly-3-hydroxybutyrate have a great potential for suppressing or inhibiting pathogenic bacteria in the gastro intestinal tract, e.g. have a antimicrobial activity against strains of Vibrio, E. coli and Salmonella.Type: ApplicationFiled: May 1, 2007Publication date: April 15, 2010Applicant: UNIVERSITY GENTInventors: Nico Boon, Tom Defoirdt, Wim De Windt, Tom Van De Wiele, Willy Verstraete