Patents by Inventor Nico P. Ghilardi

Nico P. Ghilardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20210338778
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: January 29, 2021
    Publication date: November 4, 2021
    Inventors: Alexander R. ABBAS, Nico P. GHILARDI, Zora MODRUSAN, Dimitry M. DANILENKO, Frederic J. DE SAUVAGE, Wenjun OUYANG, Patricia A. VALDEZ, Yan ZHENG
  • METHOD OF TREATING AUTOIMMUNE INFLAMMATORY DISORDERS USING IL-23R LOSS-OF-FUNCTION MUTANTS
    Publication number: 20140037618
    Abstract: The present invention relates to compositions and methods of diagnosing and treating autoimmune and inflammatory disorders that are characterized by IL-23R loss-of-function mutations.
    Type: Application
    Filed: May 24, 2013
    Publication date: February 6, 2014
    Inventors: Svetlana Pidasheva, Hilary Clark, Nico P. Ghilardi, Timothy W. Behrens, Hergen Spits, Sara Trifari
  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20130052159
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 28, 2013
    Inventors: Alexander R. Abbas, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20110280828
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: May 20, 2011
    Publication date: November 17, 2011
    Inventors: Alexander R. ABBAS, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • USE OF IL-27 ANTAGONISTS TO TREAT LUPUS
    Publication number: 20100297127
    Abstract: This invention relates to methods of treating the autoimmune disorder lupus with IL-27 antagonists, as well as articles of manufacture comprising IL-27 antagonists. The invention also relates to methods and kits for identifying patients that are likely to respond to an IL-27 antagonist treatment.
    Type: Application
    Filed: April 8, 2010
    Publication date: November 25, 2010
    Inventors: Nico P. GHILARDI, Marcel L. BATTEN, Jason A. HACKNEY
  • Compositions and methods for treatment of microbial disorders
    Publication number: 20090202475
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: November 7, 2008
    Publication date: August 13, 2009
    Applicant: Genentech, Inc.
    Inventors: Alexander R. Abbas, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • Nucleic acid encoding novel type-1 cytokine receptor GLM-R
    Patent number: 7303896
    Abstract: The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: December 4, 2007
    Assignee: Genentech, Inc.
    Inventors: Nico P. Ghilardi, Frederic J. de Sauvage, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin Gurney, William I. Wood