Abstract: The invention provides an apparatus for combined imaging and analyzing of a biological structure by means of ultrasonic and spectroscopic techniques. The inventive diagnostic apparatus is adapted for simultaneous acquisition of ultrasonic echo signals and surface enhanced Raman spectroscopic signals. The invention makes particular use of a contrast agent that on the one hand provides enhanced reflection efficiency for ultrasonic echo signals and on the other hand enables surface enhanced Raman spectroscopy. The contrast agent comprises conventional microbubbles as well as solid metal nano-particles or combinations thereof. The invention therefore effectively provides non-invasive in vivo analysis of blood as well as detection and visualization of a blood flow.

Abstract: A flexible flat panel display which exhibits fabric-like behavior, comprising a substrate (10) formed of an elastomeric material, preferably with a layer of textile material (14) embedded therein. The substrate (10) is arranged and configured so as to have a modulus of elasticity such that the display can be curved over at least two radii of curvature simultaneously and/or stretched in one or more directions under normal working conditions. The resultant display can be incorporated into, for example, clothing and the like. A method of manufacturing a flexible flat panel display is also described.