Patents by Inventor Nicolò Miraglia

Nicolò Miraglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof
    Patent number: 9718947
    Abstract: A process for the preparation of a chondroitin sulphate salt with an average molecular weight (Mw) of 10-30 kDa via chemical sulphation of an unsulphated chondroitin backbone is provided. The unsulphated chondroitin can be obtained by acid hydrolysis of a capsular polysaccharide K4 made directly from E. coli strain O5:K4:H4 or directly produced from a genetically modified strain of E. coli. Sulphation of the N-acetyl-D-galactosamine residue at position 4 or 6 takes place simultaneously in the same polysaccharide chain, simulating the sulphation pattern observed in natural chondroitin sulphate.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: August 1, 2017
    Assignee: Gnosis S.p.A.
    Inventors: Davide Bianchi, Marco Valetti, Paola Bazza, Nicolò Miraglia, Ermanno Valoti