Patents by Inventor Nicola Dioguardi

Nicola Dioguardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8503798
    Abstract: The present invention relates to a method and an apparatus for processing and metrically quantifying images of objects containing clusters of points/spots, such as biological specimens comprising cluster of cells, in particular of human or animal origin, or images thereof.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: August 6, 2013
    Assignee: Humanitas Mirasole S.p.A.
    Inventors: Nicola Dioguardi, Carlo Russo, Fabio Grizzi, Barbara Franceschini
  • Patent number: 8094915
    Abstract: The present invention relates to an “in vitro” diagnostic method for diseases affecting human or animal tissues, in particular for the diagnosis of diseases involving inflammation and fibrosis in human or animals, more particularly for liver diseases.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: January 10, 2012
    Assignee: Humanitas Mirasole S.p.A.
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini
  • Patent number: 7596250
    Abstract: The present invention relates to a method and an apparatus for processing images of irregularly shaped objects, such as biological specimens, in particular of human or animal origin, or images thereof. The metric quantification of a biological body part or tissue or of an abnormal material spot or aggregate contained therein is also performed by means of the invention method. In particular, the present invention relates to a method for processing images of irregularly shaped objects, comprising a stage of acquisition of a digital image of said object, a stage of image elaboration (IMAEL) for quantifying said digital image to 1 bit and a stage of metrical processing of said 1-bit quantized image, wherein said stage of metrical processing comprises: —) a stage of object's metrical quantification (QUANT) for determining Euclidean perimeter P and/or area A of said object; —) a stage of dimensional calculation (DIM-CLC) for calculating a fractal-corrected perimeter Pf and/or area Af of said object.
    Type: Grant
    Filed: November 19, 2002
    Date of Patent: September 29, 2009
    Assignee: Humanitas Mirasole S.P.S.
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini
  • Publication number: 20090232382
    Abstract: The present invention relates to an “in vitro” diagnostic method for diseases affecting human or animal tissues, in particular for the diagnosis of diseases involving inflammation and fibrosis in human or animals, more particularly for liver diseases.
    Type: Application
    Filed: June 5, 2006
    Publication date: September 17, 2009
    Applicant: HUMANITAS MIRASOLE S.p.A.
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini
  • Publication number: 20090022388
    Abstract: The present invention relates to a method and an apparatus for processing and metrically quantifying images of objects containing clusters of points/spots, such as biological specimens comprising cluster of cells, in particular of human or animal origin, or images thereof.
    Type: Application
    Filed: February 28, 2006
    Publication date: January 22, 2009
    Inventors: Nicola Dioguardi, Carlo Russo, Fabio Grizzi, Barbara Franceschini
  • Publication number: 20060281169
    Abstract: The present invention relates to an analytical device (1) for cell cultures comprising a container (4) for cell cultures, a reservoir (2) for the storage of fresh culture medium for said cell cultures, pumping means (3) suitable to introduce said fresh culture medium into said container and to remove metabolised culture medium from the cell cultures of said of said container and a depositing device (5) suitable for depositing the metabolised culture medium removed from said container by means of said pumping means onto an analytical support (11).
    Type: Application
    Filed: June 14, 2005
    Publication date: December 14, 2006
    Applicant: HUMANITAS MIRASOLE S.p.A.
    Inventors: Luciano Parmeggiani, Nicola Dioguardi, Fabio Grizzi
  • Publication number: 20060251311
    Abstract: The present invention relates to a method and an apparatus for processing images of biological tissues, in particular of human or animal origin. The metric quantification of a biological body part or tissue or of an abnormal material spot or aggregate contained therein is also performed by means of the invention method. The method according to the invention is applied in particular to the Computed Axial Tomography technique.
    Type: Application
    Filed: July 22, 2003
    Publication date: November 9, 2006
    Applicant: HUMANITAS MIRASOLE S.p.A.
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini, Piercarlo Muzzio
  • Publication number: 20060228008
    Abstract: The present invention relates to a method and an apparatus for processing images of irregularly shaped objects, such as biological specimens, in particular of human or animal origin, or images thereof. The metric quantification of a biological body part or tissue or of a material spot or aggregate of any origin which is contained therein is also performed by the present invention method. In particular, the method of the present invention is applied to the “confocal microscopy” technique. In particular, the present invention relates to a method of processing digital images including one or more objects to be quantified, the method including normalization of the digital images and quantization of the images to one bit.
    Type: Application
    Filed: July 9, 2003
    Publication date: October 12, 2006
    Applicant: HUMANITAS MIRASOLE S.p.A.
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini, Paolo Vinciguerra, Ingrid Torres-Munoz
  • Publication number: 20050254710
    Abstract: The present invention relates to a method and an apparatus for processing images of irregularly shaped objects, such as biological specimens, in particular of human or animal origin, or images thereof. The metric quantification of a biological body part or tissue or of an abnormal material spot or aggregate contained therein is also performed by means of the invention method. In particular, the present invention relates to a method for processing images of irregularly shaped objects, comprising a stage of acquisition of a digital image of said object, a stage of image elaboration (IMAEL) for quantifying said digital image to 1 bit and a stage of metrical processing of said 1-bit quantized image, wherein said stage of metrical processing comprises: -) a stage of object's metrical quantification (QUANT) for determining Euclidean perimeter P and/or area A of said object; -) a stage of dimensional calculation (DIM-CLC) for calculating a fractal-corrected perimeter Pf and/or area Af of said object.
    Type: Application
    Filed: November 19, 2002
    Publication date: November 17, 2005
    Inventors: Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Barbara Franceschini
  • Patent number: 4473081
    Abstract: A multichannel programmable band comparator is provided for apparatus used in cardiac surgery. A plurality of transducers supply signals relating to parameters such as the blood flow, arterial and venal pressure, body temperature and acid-base equilibrium to a multiplexer. The multiplexer supplies an analog-to-digital converter which is connected to a comparator. The comparator receives upper and lower limit values which are preset in a memory and operates a visual and acoustic alarm via a demultiplexer if any parameter is outside the band defined by the corresponding upper and lower limit values. The multichannel comparator may be used during open heart surgery, when the cardiocirculatory and respiratory functions of a patient are taken over by complex apparatus, to ensure that various physiological parameters remain within acceptable limits.
    Type: Grant
    Filed: May 8, 1981
    Date of Patent: September 25, 1984
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: Nicola Dioguardi, Elena Allorio, Mila Bertinetti