Patents by Inventor Nicola Diulgheroff

Nicola Diulgheroff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9718829
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: August 1, 2017
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof
    Publication number: 20170129900
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: November 23, 2016
    Publication date: May 11, 2017
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9562050
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: February 7, 2017
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof
    Publication number: 20160002253
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9156841
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: October 13, 2015
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Forms of tiotropium bromide and processes for preparation thereof
    Patent number: 9108962
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: August 18, 2015
    Assignee: Sicor, Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Novel Forms Of Tiotropium Bromide And Processes For Preparation Thereof
    Publication number: 20140323515
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 30, 2014
    Inventors: Nicola DIULGHEROFF, Francesca SCARPITTA, Alessandro PONTIROLI, Adrienne KOVACSNE-MEZEI, Judith ARONHIME, Alexandr JEGOROV
  • Forms of tiotropium bromide and processes for preparation thereof
    Patent number: 8846926
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: September 30, 2014
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • NOVEL FORMS OF TIOTROPIUM BROMIDE AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20140057935
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: October 31, 2013
    Publication date: February 27, 2014
    Applicant: SCIOR INC.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexander Jegorov
  • Processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid
    Patent number: 8629152
    Abstract: Provided are processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid, in particular, pemetrexed disodium salt, directly from pemetrexed diacid or salts thereof, i.e., without isolating the obtained pemetrexed salt prior to lyophilizing it.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 14, 2014
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Zvi Harel
  • Process for the preparation of tiotropium bromide
    Patent number: 8378103
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: February 19, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Processes for preparing intermediates of pemetrexed
    Patent number: 8362245
    Abstract: Provided are processes for preparing intermediates of pemetrexed.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: January 29, 2013
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Zrinski Villa
  • Process for the preparation of tiotropium bromide
    Patent number: 8344143
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: January 1, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • NOVEL FORMS OF TIOTROPIUM BROMIDE AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20120165364
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: March 5, 2012
    Publication date: June 28, 2012
    Applicant: SICOR INC.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • NOVEL FORMS OF TIOTROPIUM BROMIDE AND PROCESSES FOR PREPARATION THEREOF
    Publication number: 20120108625
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: December 28, 2011
    Publication date: May 3, 2012
    Applicant: SICOR INC.
    Inventors: Nicola DIULGHEROFF, Francesca SCARPITTA, Alessandro PONTIROLI, Adrienne KOVACSNE-MEZEI, Judith ARONHIME, Alexandr JEGOROV
  • Forms of tiotropium bromide and processes for preparation thereof
    Patent number: 8163913
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: April 24, 2012
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 8088919
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 3, 2012
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • PROCESSES FOR PREPARING INTERMEDIATES OF PEMETREXED
    Publication number: 20110263851
    Abstract: Provided are processes for preparing intermediates of pemetrexed.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 27, 2011
    Applicant: SICOR INC.
    Inventors: Nicola DIULGHEROFF, Moran PIRKES, Alessandro PONTIROLI, Marco VILLA
  • CRYSTALLINE FORMS OF PEMETREXED DIACID AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20110196155
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: March 23, 2011
    Publication date: August 11, 2011
    Applicant: SICOR INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Csilla Nemethne Racz, Moran PIRKES, Alessandro PONTIROLI, Marco VILLA, Judith ARONHIME
  • Processes for preparing intermediates of pemetrexed
    Patent number: 7994180
    Abstract: The invention provides intermediates of pemetrexed of formula VI and processes for the preparation thereof.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: August 9, 2011
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa