Patents by Inventor Nicola Murdoch Heron

Nicola Murdoch Heron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treatment using N-(3-fluorophenyl)-2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-quinazolin-4-yl)amino]-1H-pyrazol-5-yl}acetamide
    Patent number: 9567358
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: February 14, 2017
    Assignee: AstraZeneca AB
    Inventors: Nicola Murdoch Heron, Frederic Henri Jung, Andrew Mortlock, Georges Pasquet
  • CHEMICAL COMPOUNDS
    Publication number: 20150307534
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Application
    Filed: March 18, 2015
    Publication date: October 29, 2015
    Applicant: AstraZeneca AB
    Inventors: Nicola Murdoch HERON, Frederic Henri JUNG, Andrew MORTLOCK, Georges PASQUET
  • Phosphonoxy quinazoline derivatives and their pharmaceutical use
    Patent number: 9018191
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: April 28, 2015
    Assignee: AstraZeneca AB
    Inventors: Nicola Murdoch Heron, Andrew Austen Mortlock, Frederic Henri Jung, Georges Rene Pasquet
  • PHOSPHONOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
    Publication number: 20140162984
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Application
    Filed: August 21, 2012
    Publication date: June 12, 2014
    Applicant: ASTRAZENECA AB
    Inventors: Nicola Murdoch HERON, Andrew Austen MORTLOCK, Frederic Henri JUNG, Georges Rene PASQUET
  • Phosphonoxy quinazoline derivatives and their pharmaceutical use
    Patent number: 8268841
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Grant
    Filed: April 28, 2009
    Date of Patent: September 18, 2012
    Assignee: Astrazeneca AB
    Inventors: Nicola Murdoch Heron, Andrew Austen Mortlock, Frederic Henri Jung, Georges Rene Pasquet
  • Compound—827
    Patent number: 8008279
    Abstract: The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: August 30, 2011
    Assignee: AstraZeneca AB
    Inventors: Alexander Graham Dossetter, Nicola Murdoch Heron
  • Chemical compounds
    Patent number: 7691867
    Abstract: Quinazoline derivatives of formula (I); for use in the treatment of proliferative diseases such as cancer and in the preparation of medicaments for use in the treatment of proliferative diseases, and to process for their preparation, as well as pharmaceutical compositions containing them as active ingredient.
    Type: Grant
    Filed: April 14, 2004
    Date of Patent: April 6, 2010
    Assignee: AstraZeneca AB
    Inventors: Nicola Murdoch Heron, Georges Rene Pasquet, Andrew Austen Mortlock, Frederic Henri Jung
  • PHOSPHONOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
    Publication number: 20100069412
    Abstract: Quinazoline derivatives of formula (I): wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Application
    Filed: April 28, 2009
    Publication date: March 18, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Nicola Murdoch Heron, Andrew Austen Mortlock, Frederic Henri JUNG, Georges Rene PASQUET
  • Phosphonooxy quinazoline derivatives and their pharmaceutical use
    Patent number: 7528121
    Abstract: Quinazoline derivatives of formula (I) wherein A is 5-membered heteroaryl containing a nitrogen atom and one or two further nitrogen atoms; compositions containing them, processes for their preparation and their use in therapy.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: May 5, 2009
    Assignee: AstraZeneca AB
    Inventors: Nicola Murdoch Heron, Andrew Austen Mortlock
  • Novel Compound - 827
    Publication number: 20090012077
    Abstract: The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
    Type: Application
    Filed: June 25, 2008
    Publication date: January 8, 2009
    Inventors: Alexander Graham Dossetter, Nicola Murdoch Heron